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En Route to multiphasic anthropomorphic MR phantoms: An additive manufacturing approach applying silicone 3D-printing techniques
Wolfgang Kilian1, Rüdiger Brühl1, Yasser Abdulhadi1, and Bernd Ittermann1
1Physikalisch-Technische Bundesanstalt (PTB), Berlin, Germany
Silicone additive manufacturing is a potential new technique to generate 'on-demand' anthropomorphic MR-phantoms. T1 relaxation could be as high as one second. T2 relaxation, however, exhibits a more complex behavior with a fast and slow component in the range of 20 and 100 ms, respectively.
Figure 4: First 3D-printed silicone test samples commercially printed. Top left: 3D-model of the dataset provided to the companies with a small brain segment (red: white matter, green: gray matter) and two added homogenous blocks. Top right: photograph of the samples as produced by ACEO, EnvisionTEC and SanDraw, respectively (numbers show the Shore-A hardness of the used in-house silicone type). Second row: SE-image with TE = 13 ms; third row: T1 images; fourth row: T2 images for the fast-relaxing component; last row: T2 images of the slow relaxing component – not seen in the ACEO sample.
Figure 1: Result of adapted segmentation workflow to achieve a minimal structure size of 2 mm (white matter in yellow, gray matter dark blue) and a closed scull (green) which has a single opening for filling the voids with CSF mimicking liquid.