Ghoncheh Amouzandeh1, Dariya I Malyarenko1, Yuxi Pang1, Brian D Ross1, and Thomas L Chenevert1
1Radiology, University of Michigan, Ann arbor, MI, United States
1Radiology, University of Michigan, Ann arbor, MI, United States
Temperature and concentration dependence of apparent diffusion coefficient for 0-50% PVP were studied for scanner room temperature range. Consistent with Arrhenius model, we showed that collision frequency factor and activation energy increase linearly with increasing [PVP] from 10-40%.
Figure 1: PVP phantom structure a) 1H
image showing tube positions b) ADC map c) signal decay vs increasing b values
for water tube at the center of phantom exhibits noise-floor bias for
b>1000 s/mm2 (excluded from ADC fit)
Figure 2: ADC values for each PVP
concentration at three measured temperatures. Doted lines display the linear
fits to the data. Using linear regression, fit coefficients C1 and C2 are
extracted for each line and tabulated.