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Feasibility of white matter Standard Model parameter estimation in clinical settings

Santiago Coelho¹, Steven Baete¹, Gregory Lemberskiy¹, Benjamin Ades-aron¹, Jelle Veraart¹, Dmitry S. Novikov¹, and Els Fieremans¹
¹Radiology, NYU School of Medicine, New York, NY, United States

We apply optimal scanner-specific diffusion protocols to estimate microstructural parameters in 15 minutes with clinical scanners. We show reproducible scan-rescan results and assess inter-scanner variability.

Parametric maps of f shown for all protocols and scanners.

Standard model parametric maps for one of the subjects. A WM ROI extracted from the JHU WM atlas is drawn on top of the map. Bottom row shows the corresponding parametric histograms for the plotted ROI.