Robust spatial and temporal unwrapping for accurate quantitative susceptibility mapping
Alex Ensworth1, Véronique Fortier1,2, Jorge Campos Pazmino1, and Ives R Levesque1,2,3,4
1Medical Physics Unit, McGill University, Montreal, QC, Canada, 2Biomedical Engineering, McGill University, Montreal, QC, Canada, 3Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 4Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, Canada
Quality-guided region-growing phase unwrapping with temporal median phase restoration is more accurate than Laplacian-based methods for quantitative susceptibility mapping.
Five echoes after QGRG spatial unwrapping are shown across the columns. From left to right, the first echo is at 5.0 ms, followed by 10.4 ms, 15.8 ms, 21.2 ms and then 26.6 ms. The top row is without temporal unwrapping (TU), the middle row is with temporal unwrapping and the bottom row is a plot of the line profiles for each column. Dataset C2 was used.
Six different techniques (three Laplacian, top row, and three path-following, bottom row) were used to spatially unwrap phase data from dataset C2. The output from each unwrapping technique is shown with an axial cross-section of the brain, and a line profile beneath it. Panel A represents the Laplacian from the STI suite, B is the Laplacian from the MEDI toolbox, C is the Laplacian from a collaborator, D represents QGRG, E represents SEGUE and F represents region growing from the MEDI toolbox.