Feasibility of Xenon Polarization Transfer Contrast Imaging using Continuous RF Irradiation
Faraz Amzajerdian1, Tahmina Achekzai1, Luis Loza1, Hooman Hamedani1, Yi Xin1, Harilla Profka1, Ian Duncan1, Stephen Kadlecek1, Kai Ruppert1, and Rahim Rizi1
1University of Pennsylvania, Philadelphia, PA, United States
XTC MRI with continuous
RF irradiation produces depolarization distributions similar to those obtained
with pulsed saturation schemes, but with a significant time advantage that
decreases required breath-hold durations.
Figure 2: Depolarization maps in a healthy rat and corresponding
boxplots for 500 ms TP saturations with increasing flip angles.
Figure 3: Depolarization maps for RBC saturations in a healthy
rat, comparing equivalent flip angle per ms saturations with multiple, shorter
pulses (< 0.3 ms delay in-between). For example, the first column is: one
100 ms pulse (flip angle 18,000°) vs. two 50 ms pulses (flip angle 9,000° each)
vs. four 25 ms pulses (flip angle 4,500° each).