Time-averaged wall shear stress: a potential indicator for carotid intra-plaque hemorrhage
Rui Shen1, Huiyu Qiao1, Zihan Ning1, Dongye Li2, Dandan Yang1, and Xihai Zhao1
1Center for Biomedical Imaging Research, Tsinghua University, Beijing, China, 2Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
In this study, TAWSS was found to be associated
with carotid IPH. In discriminating carotid IPH, the strength of combination
between TAWSS and plaque burden was higher than each measurement alone, which suggests that TAWSS is a potential indicator for carotid vulnerable
plaque features of IPH.
Figure 1. The demonstration of CFD analysis
parameters, to multi-contrast MRI images and histological images.
Figure 2. ROC curves of TAWSS combined with max
wall thickness (MWT) and normal wall index (NWI) in discriminating IPH.
(The black
line represents the ROC curves for predicting IPH with TAWSS. The orange and
green lines represent the ROC curves for predicting IPH with TAWSS of combined
MWT and of combined NWI.)