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Assessment of myocardial involvement characteristics by cardiac MR imaging in patients with polymyositis and dermatomyositis
Changjing Feng1, Wangyan Liu1, Xiaoxuan Sun1, Qiang Wang1, Xiaomei Zhu1, Xiaoyue Zhou2, Yi Xu1, and Yinsu Zhu1
1The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2Siemens Healthineers Ltd., Shanghai, China
CMR tissue characterization imaging could early detect myocardial involvement in the PM and DM patients. The features of myocardial involvement are  different between PM and DM patients. Myocardial involvement in patients with PM is more serious when compared to patients with DM.
Course of late gadolinium enhancement (LGE), Native myocardial T1 and ECV map images in PM and DM patients, respectively. LGE detected mid-wall enhancement in the interventricular septum and inferior in PM and subepicardial enhancement in the interventricular septum and inferior in DM. LGE volume of 16% in both the PM and DM patients. Mean global native T1 and ECV values were 1281 ms and 32%, 1283 ms and 30% in PM and DM patients, respectively.
Global native T1 (A) in control (green), Polymyositis (PM) (red), and Dermatomyositis (DM) (blue) and global ECV (B) in Polymyositis (PM) (red), and Dermatomyositis (DM) (blue) showed by box plots.