Evaluation of bone marrow infiltration in the newly diagnostic Multiple Myeloma with Intravoxel Incoherent Motion Diffusion-weighted MRI
Xiaojiao Pei1, Tao Jiang1, Zhenyu Pan1, Yufei Lian1, Yueluan jiang2, and qinglei Shi 3
1Radiology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China, 2MR Scientific Marketing, Diagnosis Imaging, Siemens Healthineers China, Beijing, China, 3Scientific Marketing, Diagnosis Imaging, Siemens Healthineers China, Beijing, China
This
study used IVIM parameters to quantitatively diagnose MM vertebral bone marrow and normal bone marrow. For diagnosing MM patients from healthy
volunteers, the D showed
the highest sensitivity was 90.0%,
and its Specificity was
94.7%,with the cutoff value of 141.8×10-3㎜2/s.
Fig1. Exemplary Sagittal IVIM parametric maps
of lumbar
spine in NDMM group and healthy group.
Fig3. Analysis
of ROC curve between ADC, D and D*.
The
area under the receiver operating characteristic (ROC) curve of ADC, D and D* were
0.935±
0.037, 0.944± 0.034, and 0.935± 0.036, respectively. Among these, the IVIM-dfast
showed the highest sensitivity was 90.0%,
and its Specificity
was
94.7%, with the cutoff value of 141.8×10-3㎜2/s.