3667
Evaluation of bone marrow infiltration in the newly diagnostic Multiple Myeloma with Intravoxel Incoherent Motion Diffusion-weighted MRI
Xiaojiao Pei1, Tao Jiang1, Zhenyu Pan1, Yufei Lian1, Yueluan jiang2, and qinglei Shi 3
1Radiology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China, 2MR Scientific Marketing, Diagnosis Imaging, Siemens Healthineers China, Beijing, China, 3Scientific Marketing, Diagnosis Imaging, Siemens Healthineers China, Beijing, China
This study used IVIM parameters to quantitatively diagnose MM vertebral bone marrow and normal bone marrow. For diagnosing MM patients from healthy volunteers, the D showed the highest sensitivity was 90.0%, and its Specificity was 94.7%,with the cutoff value of 141.8×10-3㎜2/s.
Fig1. Exemplary Sagittal IVIM parametric maps of lumbar spine in NDMM group and healthy group.
Fig3. Analysis of ROC curve between ADC, D and D*. The area under the receiver operating characteristic (ROC) curve of ADC, D and D* were 0.935± 0.037, 0.944± 0.034, and 0.935± 0.036, respectively. Among these, the IVIM-dfast showed the highest sensitivity was 90.0%, and its Specificity was 94.7%, with the cutoff value of 141.8×10-3㎜2/s.