Lei Wang1, Longxiao Wei1, and Menghui Yuan1
1Nuclear Medicine, Tangdu Hospital of Air Force Medical University, Xi'an, China
1Nuclear Medicine, Tangdu Hospital of Air Force Medical University, Xi'an, China
Metabolic effective connection method based on integrated PET/MR technology gives more consistent directional pathways than granger causality. Metabolic effective connection is more suitable for region-wise study.
Fig3. The group-wise directional pathways identified by Metabolic effective connection(MEC) method. Arrows represent the direction of the pathways. The line thickness represents the relative strength of the MEC. There were more bidirectional interactions between NAc and caudate, and the unidirectional pathway from OFC to caudate revealed the regulation in frontostriatal dopamine pathway. (One-sample t-test, p<0.05, fdr correted)
Fig2. The group-wise directional network identified by Granger causality. Arrows represent the direction of the pathways. The line thickness represents the relative strength of the granger causality index of that pathway. The SN and thalamus were almost isolated from other nucleus and cortex. Bidirectional connection were identified between the right OFC and left NAc. (One-sample Wilcoxcon signed rank test, p<0.05, fdr corrected)