Luigi Lorenzini¹, Silvia Ingala¹, Alle Meije Wink¹, Joost PA Kuijer¹, Viktor Wottschel¹, Carole Sudre^2,3,4,5, Sven Haller^6,7, José Luis Molinuevo^8,9,10,11, Juan Domingo Gispert^8,10,11,12, David M Cash¹³, David L Thomas¹⁴, Sjoerd B Vos^14,15, Ferran Prados Carrasco^16,17,18, Jan Petr¹⁹, Robin Wolz^20,21, Alessandro Palombit²⁰, Adam J Schwarz²², Gael Chételat²³, Pierre Payoux^24,25, Carol Di Perri²¹, Cyril Pernet²⁶, Frisoni Giovanni^27,28, Nick C Fox¹³, Craig Ritchie²⁹, Joanna Wardlaw^26,30, Adam Waldman^26,31, Frederik Barkhof^1,32, and Henk JMM Mutsaerts^1,33
1VUmc Amsterdam, Amsterdam, Netherlands, ²MRC unit for Lifelong Health and Ageing at UCL, London, London, United Kingdom, ³Department of Neurodegenerative Disease, Dementia Research Centre, London, United Kingdom, ⁴Centre for Medical Image Computing UCL, London, United Kingdom, ⁵School of Biomedical Engineering & Imaging Sciences, King’s College London, London, United Kingdom, ⁶CIRD Centre d’Imagerie Rive Droite, Geneva, Switzerland, ⁷Department of Surgical Sciences, Radiology, Uppsala University, Uppsala, Sweden, ⁸Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain, ⁹CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain, ¹⁰IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain, ¹¹Universitat Pompeu Fabra, Barcelona, Spain, ¹²CIBER Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain, ¹³Department of Neurodegenerative Disease, Dementia Research Centre, UCL, London, United Kingdom, ¹⁴Neuroradiological Academic Unit, UCL Queen Square Institute of Neurology, London, United Kingdom, ¹⁵Centre for Medical Image Computing, University College London, London, United Kingdom, ¹⁶Nuclear Magnetic Resonance Research Unit, Queen Square Multiple Sclerosis Centre, University College London Institute of Neurology, London, United Kingdom, ¹⁷Department of Medical Physics and Biomedical Engineering, Centre for Medical Image Computing, University College London, London, United Kingdom, ¹⁸e-Health Centre, Open University of Catalonia, Barcelona, Spain, ¹⁹Helmholtz‐Zentrum Dresden‐Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany, ²⁰IXICO, London, United Kingdom, ²¹Imperial College London, London, United Kingdom, ²²Takeda Pharmaceuticals Ltd., Cambridge, MA, United States, ²³Université de Normandie, Unicaen, Inserm, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders", institut Blood-and-Brain @ Caen-Normandie, Cyceron, Caen, France, ²⁴Department of Nuclear Medicine, Toulouse CHU, Purpan University Hospital, Toulouse, France, ²⁵Toulouse NeuroImaging Center, University of Toulouse, INSERM, UPS, Toulouse, France, ²⁶Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, Scotland, ²⁷Laboratory Alzheimer’s Neuroimaging & Epidemiology, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy, ²⁸University Hospitals and University of Geneva, Geneva, Switzerland, ²⁹Centre for Dementia Prevention, The University of Edinburgh, Edinburgh, Scotland, ³⁰UK Dementia Research Institute at Edinburgh, University of Edinburg, Edinburgh, Scotland, ³¹Department of Medicine, Imperial College London, London, United Kingdom, ³²Institute of Neurology and Healthcare Engineering, University College London, London, United Kingdom, ³³Ghent Institute for Functional and Metabolic Imaging (GIfMI), Ghent University, Ghent, Belgium

We developed a semi-automated pipeline for the management of multi-modal MRI data acquired in mutli-center research studies, including processing, quality control of raw MRI data and computation of image-derived phenotypes.