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Glioblastoma grading using perfusion parameters: comparing quantitative transport mapping method and kinetic modeling method
Qihao Zhang1, Gloria Chia-Yi Chiang2, Thanh Nguyen2, Pascal Spincemaille2, and Yi Wang1
1Cornell University, New York, NY, United States, 2Weill Cornell Medical College, New York, NY, United States
QTM method can be applied to glioblastoma grading to eliminate the artery input function (AIF) dependency of kinetic modeling method.
DCE MRI of a grade IV glioblastoma (figure a). (b) and (c) Ktrans and Ve using feeding artery of the tumor, respectively. (d) sampled AIF. (e) QTM velocity magnitude map. (f) and (g) Ktrans and Ve using carotid artery of the tumor, respectively. (h) sampled AIF.
DCE MRI of a grade II glioblastoma (figure a). (b) and (c) Ktrans and Ve using feeding artery of the tumor, respectively. (d) sampled AIF. (e) QTM velocity magnitude map. (f) and (g) Ktrans and Ve using carotid artery of the tumor, respectively. (h) sampled AIF.