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DiffusionGo: A fully automatic fiber tracking software for neurosurgeon
Shin Tai Chong1, Jianping Song2, Kuan-Tsen Kuo3, Yu-Ting Ko3, Sanford PC Hsu4, Jinsong Wu2, and Ching-Po Lin1
1Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, 2Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China, 3ABC Solution Co., Ltd, Shanghai, China, 4Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
DiffusionGo is an in-house developed software specially designed for neurosurgeons, which integrated a reliable pre-processing pipeline, fully automatically fiber reconstruction algorithm, and multimodalities imaging information to achieve easy modeling and precision surgery. 
Multimodalities integration in a 60-year-old male with left frontal bAVM in DiffusionGo. S1 and S2 Speech arrest was defined as discontinuation in number counting without simultaneous motor response by DCS (a). AF (red), SLF II (green), and posterior segment of SLF (yellow) were automatically reconstructed (d). Comparing with language BOLD functional activation (c), Tract-based cortical termination (AF termination in red; SLF II termination in green; orange color represented the overlap of AF and SLF II) has more sensitivity to manifest with DCS results (e).
A 41-year-old female with temporal lobe glioblastoma was reconstructed and displayed in DiffusionGo. Cortical surface (white), blood vessel (gold), tumor (green), and peritumoral edema (light blue with translucent) were integrated (a). The lateral view and superior view of the tumor, dorsal language pathway (AF, red; SLF II, green), and ventral language pathway (IFL, light blue; IFOF, light green; UF, pink). The termination projection of AF was shown in d. Superior displacement of left Wernicke’s area was identified with intact AF projecting to left premotor and left Broca areas.