3917
The combined value of DKI and DSC MRI in differentiating high-grade glioma recurrence from pseudoprogression
Yan Tan1, Wenwei Shi2, Xiaochun Wang1, and Hui Zhang1
1Department of Radiology, First Hospital of Shanxi Medical University, Taiyuan, China, 2Department of Radiology, Zhongda Hospital, Southeast University, Nanjing, China
rMK can differentiate recurrent tumor from pseudoprogression with high diagnostic accuracy, and its application value is similar to that of rCBV. The combination of rMK and rCBV improves diagnostic performance compared to either technique alone.
ROC curves of DKI and DSC MRI parameters for differentiating glioma recurrence from pseudoprogression.
A 21-year-old man with tumor recurrence confirmed by repeat surgery was initially a high-grade glioma (WHO IV). An increasing enhanced lesion in the right frontal and temporal lobes was detected on CE-T1WI with increased CBV, CBF, MTT, TTP, MK, Ka and Kr values, except for MD and FA values.