Whole brain CSF segmentation for consistent zero-referencing and longitudinal study applicability of MEDI+0
    
 
    Alexey Dimov1, Thanh Nguyen1, Susan Gauthier2, and Yi Wang3
1Radiology, Weill Cornell Medicine, New York, NY, United States, 2Neurology, Weill Cornell Medicine, New York, NY, United States, 3Weill Cornell Medicine, New York, NY, United States
    
        The role of CSF segmentation for zero-referenced MEDI+0 is demonstrated. In the present study we show that it is essential to enforce consistency in the CSF mask between different timepoints to ensure value reproducibility of the QSM
    
    
         
        
            Figure 2. Comparison of the MS lesion susceptibility trajectories estimated using CSFvent mask (left) and the full CSFbrain (right) masks. Note synchronous jumps in
measured susceptibility values occurring with CSFvent
        
     
    
         
        
            Figure 3. Comparison of the CSFvent for different datasets in longitudinal study