Impact of sustained Synovitis on Knee Joint Structural Degeneration: 4-Year MRI Data from the Osteoarthritis Initiative
Sara Ramezanpour1, Thanat Kanthawang 1,2, John Lynch 3, Thomas M Link 1, and Gabby B Joseph1
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Department of Radiology, Faculty of Medicine, Chiang Mai University, Thailand, Chiang Mai, Thailand, 3Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States
Subjects with
sustained synovitis over 4 years had significantly greater progression of
meniscus, bone marrow and
cartilage degeneration measured using semi-quantitative whole-organ magnetic
resonance imaging scores (WORMS) compared to controls without synovitis.
Figure 2. Bar graph of adjusted mean differences (age, gender, BMI) in WORMS
scores between baseline and 4 years of medial meniscus body for cases of
sustained synovitis based on definition (i) and controls. The error bars
represent 95% confidence intervals.
Figure 3. Bar graph demonstrating adjusted mean differences (age, gender,
BMI) in WORMS scores between baseline and 4 years of bone marrow edema in the lateral
tibia for cases of sustained synovitis based on definition (i) and controls. The
error bars represent 95% confidence intervals.