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Rapid fitting of Luminal Water Fraction in Prostate MRI
David Atkinson1, Fiona Gong1, Giorgio Brembilla1, and Shonit Punwani1
1Centre for Medical Imaging, University College London, London, United Kingdom
Two potential metrics are presented; the mean signal from later echoes, normalized to the median from the first echo, and, a bi-exponential fit using fixed T2s of 50 and 300ms. Initial presentation of results suggests these methods are fast and should be evaluated for clinical efficacy.
Fig 3. Images from three representative subjects.
Fig 2. Alternative fits to the same voxel. Note the fitted signals (top row) are similar but the T2 distributions (lower row) differ. LWF maps inset.