POST-ACQUISITION WATER SIGNAL REMOVAL IN 3D WATER-UNSUPPRESSED 1H-MR SPECTROSCOPIC IMAGING DATA OF THE PROSTATE
Angeliki Stamatelatou1, Diana Sima2, Sabine Van Huffel3, Sjaak Van Asten4, Arend Heerschap4, and Tom Scheenen4
1Radiology, Radboud UMC, Nijmegen, Netherlands, 2Icometrix, Leuven, Belgium, 3KU Leuven, Leuven, Belgium, 4Radboud UMC, Nijmegen, Netherlands
Water signal removal in 3D
water-unsuppressed 1H-MRSI data of the prostate is presented. Löwner
BSS and HLSVD methods were compared against conventional MRSI water suppression.
Post-acquisition water removal was successfully implemented, and the Löwner
filter showed the best performance.
Figure
1. MRS
prostate spectra from a volunteer in the frequency range 1.5 ppm to 5.5 ppm. a. Spectrum obtained with water signal suppression
b. Spectrum obtained without water
signal suppression but with water signal removal using a Löwner filter, c. Spectrum without water signal
suppression but with water signal removal using a HLSVD filter.
Table
2. Mean
values of the absolute metabolite concentrations of citrate
and choline. The bottom row presents absolute metabolite tissue concentrations reported
in reference 7. The choline values seem to
be lower compared to the literature, but this is explained by the fact that the
volunteers participated in the study were of a young age.