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Cortical microinfarcts on 7T MRI correlate with medial temporal lobe thinning in healthy aging
Shokufeh Sadaghiani1, M. Dylan Tisdall2, Sandhitsu R. Das1, David A. Wolk1, and John A. Detre1
1Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States, 2Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States
A significant negative correlation was seen between the number of cortical microinfarcts and mean parahippocampal cortical thickness. We also showed that only 26% of total CMIs visible on 7T MRI scans are also visible on 3T scans.
Figure 1. A. A cortical microinfarct visible on 7T T1-weighted MP2RAGE MRI scan. The CMI is not visible on B. 7T FLAIR MRI scan, C. 3T T1-weighted MRI scan and D. 3T FLAIR MRI scan.
Table 2. 7T and 3T MRI sequences parameters.