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Contrast enhancement of a magnetization prepared steady state sequence: an optimal control framework
Benoît Vernier1,2, Eric Van Reeth1,3, Frank Pilleul1,4, Olivier Beuf1, and Hélène Ratiney1
1CREATIS, Université de Lyon, INSA Lyon, UCBL Lyon 1, UJM Saint Etienne, Unité CNRS UMR 5220, INSERM U1206, F69621, Lyon, France, 2Siemens Healthineers, Saint-Denis, France, 3CPE, Lyon, France, 4Centre Léon Bérard, Lyon, France
A generic optimal control framework for contrast optimization in presence of a longitudinal steady state is presented. In vitro and in vivo experiments validate the improvement of the contrast-to-noise ratio per unit of time of an MP-RAGE sequence.
Figure 3: Rat 1, coronal slice, at the left side MP-RAGE with a simple inversion, at the right side MP-RAGE with a T2prep-IR, both optimized with an optimal control framework aiming at enhancing contrast between cortex and corpus callosum. Same acquisition parameters are used (segment duration: 3s, TR: 6.5ms, flip angle: 13°).
Figure 2 : Contrast-to-noise ratio over the two rats, the four segment duration and the different slices orientations