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Imaging Sign Of Edema As A Possible Diagnostic Aid For Lateral Lumbar Spinal Canal Stenosis
Shi Yin1, Dou Weiqiang2, and Ding Hongyuan1
1The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2GE Healthcare, MR Research, Beijing, P.R. China, Beijing, China
Based on the characteristic pathological change of nerve root edema in extraspinal sub-regions, conventional MR combined with quantitative MR DTI/DTT has a good performance for visualizing and quantitative diagnosis in lateral lumbar spinal canal stenosis.
The DTT abnormalities of symptomatic nerves can be classified into color hue reduction (a), sparse (b) and interruption (c). The visual abnormalities of tractography were found mainly in the extraforaminal (34 cases, 34.3%) and extraspinal (57 cases, 57.6%) region of compressed nerves.
The ROC curve for nerve edema had the highest AUC of 0.929 (95% CI 0.884 - 0.961); the cut point showed sensitivity and specificity of 85.9% and 100%, respectively. In addition to this, the ROC curve for distal FA and nerve diameter both had AUCs >0.80.