Changes in meniscus T2 relaxation times due to acute exercise in individuals with knee osteoarthritis
Ananya Goyal1, Garry Gold1, Feliks Kogan1, and Lauren Watkins1
1Stanford University, Stanford, CA, United States
Acute
exercise did not affect the meniscal T2 relaxation times in subjects with OA.
However, there were significant changes
when assessing the maximal regional T2 change in the medial or lateral menisci
of exercised subjects, which may be impacted by knee loading.
T2 relaxation times of the menisci, both medial
and lateral, of healthy volunteers were projected to a 2D plane to create T2
relaxation time maps. The map for Post-exercise was registered to Pre-exercise
using Elastix. The mean T2 relaxation time in the medial and
lateral menisci, as well as across both the menisci, was calculated.
T2
relaxation times were averaged across both the lateral and medial menisci.
There was no significant difference in the average T2 relaxation times between pre-exercise
and post-exercise scans for the Exercised and Rested groups. The Exercised leg
group had slightly lower T2 times than the Rested group for both scans, but
these differences were not statistically significant (p=0.96 for Pre-exercise
and p=0.29 for Post-exercise).