Evaluation of pharmacological hypothermia in rhesus monkey brains using diffusion MRI
Xiaodong Zhang1, Chunxia Li1, Xiaohuan Gu2, Doty Kempf1, Ling Wei2, and Shan Ping Yu2
1Yerkes Imaging Center, Emory University, Atlanta, GA, United States, 2Department of Anesthesiology, Emory University, Atlanta, GA, United States
The monkey brain and body temperatures were reduced by administration of ABS-201. Gender difference of the drug-induced hypothermia was observed. The difference of temperature reduction between the monkey brain and body were seen .
The
progressive changes of the brain and body temperatures in adult monkeys administrated with saline or the
novel neurotensin analog (ABS-201)
The Temperature (°C)
Changes in
the
Body and Brain of Each Monkey after administrated with saline or the novel neurotensin analog (ABS-201)