ISMRM22 - Renal MRI: From Nephron to k-Space

Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

Renal MRI: From Nephron to k-Space

Member-Initiated Symposium

Tuesday, 10 May 2022

ICC Capital Hall 1

09:15 - 11:15

Session Number: MIS-02

Organizers
Ilona Dekkers
Manuel Taso
Alexandra Ljimani

Overview
Renal diseases pose a significant socio-economic burden on healthcare systems. The development of better diagnostics and prognostics is well-recognized as a key strategy to resolve these challenges. Central to these developments are MRI biomarkers due to their potential for monitoring of early parenchymal changes, renal disease progression or treatment effects. The surge in renal MRI involves major cross-domain initiatives (PARENCHIMA), large clinical studies, the UK Renal Imaging Network (UKRIN) and US NIDDK initiatives. In parallel with these translational efforts, the need for greater biological specificity remains to enable engagement with renal physicians and increase the associated health impact. This MIS spotlights this issue with the goal of inspiring more solutions from the ISMRM community. Presentations are devoted to (1) educating imaging scientists and clinicians on renal physiology and clinical demands, (2) presenting the current state of leading MR surrogates in assessing renal biology as well as their next generation of innovation, and (3) describing the potential of these imaging markers for providing tissue characterization to guide or supplement clinical decision making. We hope to continue momentum of recent years and introduce new entrants to the development process, connecting (patho)physiology with (bio)physics, and conceiving new clinical applications. This MIS is wholeheartedly supported by the recently established ISMRM study group on renal MRI.

Target Audience
This MIS attracts young scientists and new entrants into the field. It targets basic scientists, engineers, translational researchers and clinicians.

Educational Objectives
As a result of attending this course, participants should be able to:
• Understand the utilization of MRI by nephrologists, in addressing current needs and possibly supplying new biomarkers to clinical use|• Understand the needs for biological validation of renal MR markers to clarify the link to biology and physiology|• Summarize the current form of current renal MRI contrasts (BOLD, perfusion, diffusion) as well as next level innovations|• Discuss the potential added value of renal MR in patient management as a supplement or alternative to current standards (eGFR, biopsy)

	09:15		Renal MRI: All a Nephrologist Could Want, or More Than They Need? Video Unavailable LaTonya Hickson Mayo Clinic, United States
	09:35		Glomerular Filtration, Tubular Function & Oxygenation: A Primer for the MR-Scientist Video Unavailable Erdmann Seeliger Charite, Germany
	09:55		Renal Functional MRI: What Are We Measuring, What Is its Added Clinical Value, & What’s Next - Intrarenal Oxygenation Video Unavailable Eric Bechler Heinrich-Heine-Universitat, Germany
	10:15		Renal Functional MRI: What Are We Measuring, What Is its Added Clinical Value, & What’s Next - Blood Flow & Perfusion Video Unavailable Eleanor Cox Sir Peter Mansfield Imaging Centre, United Kingdom
	10:35		Renal Functional MRI: What Are We Measuring, What Is its Added Clinical Value, & What’s Next - Renal Microstructure/Microcirculation Video Unavailable Julia Stabinska F.M. Kirby Research Center for Functional Brain Imaging Kennedy Krieger Institute, United States
	10:55		Renal Tissue Characterization: Traditional Invasive Biopsy vs. Virtual MR Biopsy Video Unavailable Octavia Bane Mount Sinai School of Medicine, United States