ISMRM22 - Velocity-Selective ASL: From Theory to Practice</span></div>

Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

Velocity-Selective ASL: From Theory to Practice

Member-Initiated Tutorials

Tuesday, 10 May 2022

ICC Capital Suite 17

14:30 - 16:30

Session Number: MIT-02

Overview
The primary weakness of spatially selective ASL (e.g. PCASL/PASL) is arterial transit time (ATT) from the larger arteries (labeling) to the microvasculature/tissue (imaging). As ATT is comparable to blood T1, the signal can be largely lost by the decay. Also, uncertainty in ATT complicates sequence optimization and quantification. In velocity-selective (VS) ASL, labeling based on blood velocity provides an intriguing option to overcome ATT-related issues; VS labeling works directly to the imaging volume. If the velocity encoding reaches low enough velocities, it can label the slowly moving blood of the microvasculature, eliminating any ATT. The potential benefit may be even greater outside the brain where the arterial supply is complex.
The current effort for publishing VSASL reviews/recommendations by the Perfusion Study Group makes this tutorial timely for those who apply VSASL in their research. Also, this topic is highly relevant to the ISMRM’s focus theme: Cardiovascular Imaging.
This tutorial consists of three parts. In part-1, three lecturers will provide a theoretical basis and discussion on practical issues in 1) General VSASL, 2) VS Inversion based ASL, 3) Acceleration-selective ASL. In part-2, three lectures will share their insight into the application in 4) neuro, 5) body and 6) as MRA. In hand-on in part-3, participants will learn the Bloch equation simulation of various VS labelling modules in the presence of B0/B1 inhomogeneity, eddy current and laminar flow.

Target Audience
Scientists, engineers, clinical researchers and radiologists who are interested in understanding the basics of VS-ASL and the dominant variants of VS

Educational Objectives
As a result of attending this course, participants should be able to:
Understand the basic theoretical mechanism of VS-ASL and the dominant variants of VS labeling strategies|Recognize the potentials and challenges of VS labeling strategies|Describe the suitable clinical application|Designed the Bloch equation simulation of VS labeling module for their future research

	14:30		Velocity-Selective Arterial Spin Labeling: Basics You Would Like to Know Video Unavailable Jia Guo University of California Riverside, United States
	14:45		Velocity Selective Inversion Based ASL Video Unavailable Qin Qin Johns Hopkins University
	15:00		Acceleration Selective ASL: Labeling the Arterial Blood with a Single Labeling Module Video Unavailable Sophie Schmid Leiden University Medical Center
	15:15		Clinical VSASL: Tales from Circumventing the Transit Delay Video Unavailable Divya Bolar University of California San Diego, United States
	15:30		Body Applications of VSASL Video Unavailable Dan Zhu Kennedy Krieger Institute
	15:45		Velocity-Selective MR Angiography Video Unavailable Taehoon Shin Ewha womans' university
	16:00		Hands-on: Bloch Equation Simulation of VS Labeling Video Unavailable Joseph Woods University of California San Diego, United States
	16:15		Hands-on: Bloch Equation Simulation of VS Labeling Video Unavailable Dapeng Liu Johns Hopkins University