ISMRM22 - New Tools for the Neuroradiologist: 4D Flow in the Brain

Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

New Tools for the Neuroradiologist: 4D Flow in the Brain

Sunrise Course

ORGANIZERS: Karin Markenroth Bloch, Susie Huang, Seena Dehkharghani, Anja van der Kolk

Monday, 09 May 2022

S11 (Breakout A)

08:00 - 09:00

Moderators: Susanne Schnell

Skill Level: Intermediate to Advanced

Session Number: S-M-01

Session Number: S-M-01

Overview
Brain MRI continues to be a rapidly evolving area, and it sometimes seems as if every day a new MRI technique is introduced for imaging the brain. However, how do these "hot" novel techniques work, why would we want them at all, and are they ready to be clinically implemented or still within the realms of science? In this Sunrise course, four novel and promising quantitative MRI techniques used for brain imaging will be discussed, from basic principles and technical details to (potential) clinical applications.

Target Audience
Scientists either searching for a new research field or just staying up-to-date with the latest developments in brain MRI; clinicians who wish to understand new MRI techniques, learn how they can be adapted to the brain, and how they might be applicable in clinical practice.

Educational Objectives
As a result of attending this course, participants should be able to:
- Describe the basics of MR thermometry, sodium imaging, MR elastography, and 4D flow quantification;
- Give examples of clinical cases in which these techniques can be useful; and
- Identify the limitations of each technique.

	08:00		4D Flow in Cerebrovascular Disease: How Do We Do It? View the Presentation Susanne Schnell 4D flow MRI is a phase-contrast MRI method that is time-resolved, acquired in 3D, and uses 3-directional velocity encoding to fully resolve the 3-dimensional velocity vector. Data analysis involves the correction of noise and errors, vessel segmentation, and data visualization. Applications in cerebrovascular disease include aneurysms, atherosclerotic disease, arterial-venous malformation (AVM), as well as Alzheimer's disease. Hemodynamic parameters such as flow rate, peak velocity, relative pressure, or pulsatility can be calculated from the 4D flow MRI raw data to assess e.g. the severity of stenosis or blood flow redistribution after embolization of an AVM.
	08:30		4D Flow in Cerebrovascular Disease: Why Do We Do It? View the Presentation Jeremy Collins 4D Flow MRI is a volumetric flow technique extending the 2D flow paradigm into both space and time. This method has demonstrated utility in arteriovenous malformations, intracranial atherosclerosis, intracranial venous disease, assessing abnormalities in CSF flow, and identifying high risk flow features in intracranial aneurysms. Additionally 4D flow MRI has identified new insights into potential sources of embolic stroke.