ISMRM22 - New Tools for the Neuroradiologist: Sodium Imaging in the Brain

Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

New Tools for the Neuroradiologist: Sodium Imaging in the Brain

Sunrise Course

ORGANIZERS: Karin Markenroth Bloch, Susie Huang, Seena Dehkharghani, Anja van der Kolk

Thursday, 12 May 2022

S11 (Breakout A)

08:00 - 09:00

Skill Level: Intermediate to Advanced

Session Number: S-Th-01

Session Number: S-Th-01

Overview
Brain MRI continues to be a rapidly evolving area, and it sometimes seems as if every day a new MRI technique is introduced for imaging the brain. However, how do these "hot" novel techniques work, why would we want them at all, and are they ready to be clinically implemented or still within the realms of science? In this Sunrise course, four novel and promising quantitative MRI techniques used for brain imaging will be discussed, from basic principles and technical details to (potential) clinical applications.

Target Audience
Scientists either searching for a new research field or just staying up-to-date with the latest developments in brain MRI; clinicians who wish to understand new MRI techniques, learn how they can be adapted to the brain, and how they might be applicable in clinical practice.

Educational Objectives
As a result of attending this course, participants should be able to:
- Describe the basics of MR thermometry, sodium imaging, MR elastography, and 4D flow quantification;
- Give examples of clinical cases in which these techniques can be useful; and
- Identify the limitations of each technique.

	08:00		Sodium in the Brain: How Do We Do It? View the Presentation Wafaa Zaaraoui In this presentation, we will discuss the physics and technical aspects of ²³Na MRI and provide a brief review of clinical research applications in neuroscience.
	08:30		Sodium in the Brain: Why Do We Do It? View the Presentation Daniel Paech Sodium MRI is an increasingly applied non-invasive imaging technique with a fast growing body of evidence regarding its diagnostic value, especially in neuroradiology. This lecture will discuss principle applications of Sodium-MRI at clinical and ultra-high magnetic fields (3T and 7T) providing a window into tissue metabolism and pathophysiological alteration of sodium concentrations associated with various neurological diseases. This will include applications for initial diagnosis and disease characterization (e.g. neuro-oncology, epilepsy, neurodegeneration, and neuroinflammation), prognostication, and therapy response monitoring. Difficulties regarding a broader clinical translation of sodium MRI will be discussed.