Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

2022 Joint Annual Meeting ISMRM-ESMRMB and 31st ISMRT Annual Meeting

Weekday Course

Myocardial Tissue Characterization

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Myocardial Tissue Characterization
Weekday Course
ORGANIZERS: Henrik Odéen, Mark Does, Wei-Tang Chang
Tuesday, 10 May 2022
S11 (Breakout B)
14:30 -  16:30
Moderators: 
Relaxometry: Bruce Damon
Skill Level: Intermediate
Session Number: Tu-04
 

Session Number: Tu-04

Overview
This session aims to present methods and applications of characterizing properties of the myocardium with MRI.

Target Audience
Clinicians and MR scientists/engineers interested in applying state-of-the-art MRI relaxometry, diffusion, and strain measuring methods to characterize myocardial tissue.

Educational Objectives
As a result of attending this course, participants should be able to:
- Describe the characteristics of myocardial tissue that can be investigated using MRI measures of water proton relaxation rates, water diffusion, and tissue strain & displacement;
- Identify suitable MRI methods for each of these measurements and discuss their limitations; and
- Recognize the potential roles of the methods in clinical practice.

    Relaxometry
14:30 Cardiac Relaxometry: Methods, Accuracy & Precision

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Claudia Prieto
Myocardial tissue characterisation using T1, T2, and T2* mapping has emerged as a novel extremely useful clinical adjunct enabling detection of focal and diffuse fibrosis with T1 mapping, myocardial oedema with T2 mapping, extracellular volume with pre and post T1 mapping, iron overload with T2* mapping and fat fraction with a 3-point Dixon acquisition. This talk will introduce the basics of quantitative cardiac magnetic resonance imaging, focusing mainly on myocardial T1, T2 and T2* mapping. 
15:00   Cardiac Relaxometry: Biological & Clinical Value

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Margaret Samyn
Cardiac magnetic resonance (CMR) relaxometry (including T2*, T1 and T2 mapping, as well as extracellular volume (ECV) assessment) has emerged as an accurate, reproducible, highly sensitive, and quantitative technique for characterizing diffuse myocardial processes underlying cardiac diseases. This presentation will build upon the physics of relaxometry - showing not only the biologic value of these novel CMR techniques, but their practical clinical utility in the care of patients with myocardial pathology. From hypertrophic cardiomyopathy and Duchenne muscular dystrophy to iron overload cardiomyopathy, cardiac transplant rejection and more, relaxometry is changing the way clinicians think about patient care.  
    Physical Properties
15:30   Cardiac Diffusion

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Sonia Nielles-Vallespin
The 3D microarchitecture of the myocardium underlies the mechanical and electrical properties of the heart. Cardiac Diffusion provides a non-invasive means to understand not only the dynamic changes in healthy myocardial microstructure during cardiac contraction but also the pathophysiological changes in the presence of disease. This technology offers tremendous potential to enable improved clinical diagnosis through novel microstructural and functional assessment. This talk will introduce the 3D myocardial microstructure, review in vivo cardiac diffusion methods, and clinical applications to date.
16:00   Physical Properties: Strain Imaging

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Daniel Ennis

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