Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

2022 Joint Annual Meeting ISMRM-ESMRMB and 31st ISMRT Annual Meeting

Weekend Course

Evidence in Imaging: Systematic Reviews, Meta-Analyses & White Papers

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Evidence in Imaging: Systematic Reviews, Meta-Analyses & White Papers
Weekend Course
ORGANIZERS: Udunna Anazodo, Kathryn Keenan, Richard Bowtell
Saturday, 07 May 2022
ICC Capital Suite 10-11
13:00 -  17:00
Moderators: 
Foundations of Crafting White Papers: Joseph Woods
Reviews in Practice : Lena Vaclavu
White Papers in Practice: Angel Torrado-Carvajal
Foundations of Systematic Reviews & Meta-Analyses: Flora Kennedy McConnell
Skill Level: Basic to Intermediate
Session Number: WE-10
 

Session Number: WE-10

Overview
For the past 40 years, medical practice has centered on evidence-based medicine--the use of current, best research evidence in clinical decision-making to form best practices and provide high-quality care. Systematic reviews, meta-analyses, and white papers are tools that help researchers identify the best available evidence from critical analysis of multiple studies. This course will introduce these tools for evidence-based imaging science and imaging practice and discuss rationale and how to apply these tools. Methods used to produce rigorous systematic reviews, meta-analyses, and white papers will be outlined. Examples of application of these tools in providing current MR imaging guidelines will be highlighted.

Target Audience
Radiologists, scientists, medical physicists, engineers, and clinicians at all career levels interested in methods for conducting rigorous imaging reviews and meta-analyses.

Educational Objectives
As a result of attending this course, participants should be able to:
- Explain the role of evidence summaries in imaging science and how they impact clinical practice;
- Describe differences among systematic reviews, meta-analyses, and white papers;
- Recall steps in conducting rigorous systematic review and meta-analysis from pre-registration to formulation of search strategies, to data extraction and analysis and publication guidelines;
- Describe how to organize and write white papers and implement findings in clinical workflow; and
- List ways that imaging scientists, physicists, engineers, and radiologists can work together with clinicians to close gaps between research and practice using evidence summaries.
 

    Foundations of Systematic Reviews & Meta-Analyses
13:00 The Role of Systematic Reviews & Meta-Analyses in Imaging

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Paulien Moyaert, Patricia Clement, Rik Achten, Udunna Anazodo
No one would disagree that clinical decisions should be based on the highest quality evidence. But it is simply the case that current medical practice cannot keep up with the available research. However, evidence-based medicine (EBM) does not necessarily have to be time-consuming. Practicing in an evidence-based way no longer means evaluating original research. Instead, it means finding secondary sources that give you a useful, actionable bottom line based on the evidence.In this lecture I’ll take you through the history of EBM, the EBM philosophy and the role of systematic reviews in evidence-based practice and research.
13:25 Protocols for Rigorous Imaging Systematic Reviews & Meta-Analyses

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Confidence Raymond
Systematic reviews (SR) and Meta-analysis (MA) provide high-level evidence by means of objective evaluation of all available primary studies. This evidence can influence clinical decision-making,  healthcare policy-making, and research practice. In imaging, studies involving MRI and other imaging modalities are performed using imaging protocols that are not standardized across studies. Hence, methodological rigor and complete reporting are crucial to ensure that SR & MA of imaging studies are based on the highest possible quality. This lecture will outline a step-by-step approach to performing SR and MA from problem formulation and data acquisition to quality appraisal, of studies, statistical analysis and interpretation of evidence.
    Reviews in Practice
13:50 Review in Practice: Meta-Analysis of MRI Biomarkers of Myelin

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Matteo Mancini
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14:15   Review in Practice: Cardiovascular MRI Consensus Statement

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Michael Salerno
  14:40   Break & Meet the Teachers
 
    Foundations of Crafting White Papers
15:05   When Is It Time for a White Paper?

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Matthias van Osch
In this presentation, it will be discussed when it is the right time to publish a White Paper. Timing is dependent on whether experts in the field are willing to join forces and reach consensus, whether real consensus is reached on what the right approach is, when the field is confusing for users and vendors and a white paper would provide the much needed guidance, and when the field has reached some kind of stable level, so that the White paper will not be immediately outdated.
15:30   How to Craft a White Paper

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Xavier Golay
White Papers can be a powerful means to establish an MRI method in a particular clinical applications. The writing of such consensus papers is not trivial, and may contain multiple caveats. In this presentation, I will be going through the various steps to establish such a paper, and demonstrate its potential impact.
    White Papers in Practice
15:55   White Paper in Practice: Renal Perfusion MRI Using Arterial Spin Labelling

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Maria Fernandez-Seara
The objective of this talk is to introduce and describe the methodology followed to generate the technical recommendations for acquisition, processing, and analysis of renal ASL data in the human kidney. The recommendations were developed employing a seven-stage process: (1) formation of the expert panel; (2) definition of the context of use; (3) literature review; (4) collection and comparison of MRI protocols; (5) consensus generations by an approximate Delphi method; (6) reporting of results in vendor-neutral and vendor-specific terms; (7) on-going review and updating.
16:20   White Paper in Practice: MRI Safety Recommendations

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Vikas Gulani

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