Qiu Bi¹, Kunhua Wu¹, and Yunzhu Wu^2
1the First People’s Hospital of Yunnan Province, Kunming, China, ²Siemens Healthcare, Shanghai, China

Keywords: Uterus, Tumor

In this study, we explored the value of MT imaging to characterize normal uterine structures and common uterine lesions by measuring MTR values. The results showed the MTR values were significantly different among normal uterine structures, among uterine lesions of different origin, or between some uterine lesions and corresponding normal structures. MTR values were found to be effective in the diagnosis and differential diagnosis of certain uterine diseases. It might provide a preoperative basis for neoplastic histologic origin in the uterus.

View Presentation Video

Daichi Murayama¹, Masami Yoneyama², Takayuki Sakai¹, Iain Ball³, and Shigehiro Ochi^4
1Radiology, Eastern Chiba Medical Center, Chiba, Japan, ²Philips Japan, Tokyo, Japan, ³Philips Australia & New Zealand, North Ryde, Australia, ⁴Eastern Chiba Medical Center, Chiba, Japan

Keywords: Pelvis, Diffusion/other diffusion imaging techniques

We hypothesized that LIPO-only (LION) DWI might be one of the best solutions to reduce the acquisition time of female pelvis DWI if it is further optimized to increase the robustness of fat suppression. We compared the image quality of DWI in the female pelvis between the conventional method (SPAIR-DWI) and the proposed method (LION-DWI) to investigate their clinical usefulness. LION-DWI showed correct signal decay because fat suppression pre-pulse was not applied . LION-DWI can reduce acquisition time of the pelvis DWI while maintaining the SNR and sufficient image contrast.

Haonan Zhang¹, Qingwei Song¹, Jiazheng Wang², and Ailian Liu^1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, Dalian, China, ²Philips Healthcare, Beijing, China, Beijing, China

Keywords: Pelvis, Uterus

Through the radial K-space filling, MultiVane XD(MVXD) can significantly reduce magnetic motion artefacts. As the filling percentage increases, artifacts are significantly reduced, but the scanning time gradually increases. The purpose of this study is to investigate the appropriate compressed sensing(CS) acceleration factor(AF) and filling percentage for clinical uterus T2WI.

Haini Zhang¹, Jianwei Zeng², Yankai Meng², Peng Wu³, Lu Han³, and Yinping Zhuang^4
1School of Medical Technology，Xuzhou Medical University, Xuzhou, China, ²Department of Radiology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China, ³Philips Healthcare, Shanghai, China, ⁴School of Medical Imaging, Xuzhou Medical University, Xuzhou, China

Keywords: Pelvis, Tumor

 We have compare the performance of reduced field of view （rFOV）image reconstruction using image-space sampling function （IRIS）diffusion weighted imaging （DWI）sequence and full field of view (fFOV) single-shot echo-planar imaging （SSEPI）diffusion weighted imaging（DWI）sequence for rectal cancer patients. And found that compared to fFOV ssEPI-DWI sequence, rFOV IRIS-DWI sequence has a better resolution, reduced sensitivity artifacts, image distortion, and improved image quality in rectal cancer patients.

View Presentation Video

Takahiro Ueda¹, Yoshiharu Ohno¹, Kaori Yamamoto², Natsuka Yazawa², Ikki Tozawa³, Kazuya Takeda³, Takashi Fukuba³, Masato Ikedo², Masao Yui², Hiroyuki Nagata⁴, and Hiroshi Toyama^1
1Department of Radiology, Fujita Health University School of Medicine, Toyoake, Japan, ²Canon Medical Systems Corporation, Otawara, Japan, ³Department of Radiology, Fujita Health University Bantane Hospital, Nagoya, Japan, ⁴Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University School of Medicine, Toyoake, Japan

Keywords: Pelvis, Diffusion/other diffusion imaging techniques

We hypothesized that RDC is able to improve image quality on DWI with b value with reducing distortion artifact in women’s pelvic field, when compared DWI without RDC.  The purpose of this study was to determine the capability for image quality improvements between women’s pelvic DWI with and without RDC at a 1.5 T MR system.

View Presentation Video

Ye Li¹, Ailian Liu¹, Jiazheng Wang², and Liangjie Lin^2
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Clinical and Technical Support, Philips Healthcare, Beijing, China

Keywords: Pelvis, Image Reconstruction

22 DIE patients were scanned for comparison of diagnostics accuracy between ordinary reconstruction and curved planar reconstruction image of 3D-CS-HR T2WI sequence. Results indicate that Curve images improved the detection of ectopic lesions in each ligament of the pelvic floor.

Fei Fei Zeng¹, Yun Fei Zha¹, and Weiyin Vivian Liu^2
1Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China, ²MR Research, GE Healthcare, Beijing, China

Keywords: Placenta, Placenta

Clear prenatal diagnosis and correct intraoperative treatment can ensure the safety of the fetus and pregnant women. Logistic regression analysis based on quantitative MRI parameters showed that abortion times, diameter of hyperplastic vessels in placenta and protrusion of uterus were independent risk factors for invasive placenta accreta. Diameter of hyperplastic vessels in placenta, area of low signal band on T2WI in placenta and protrusion of uterus were independent risk factors for predicting adverse clinical outcomes. Our study showed the accuracy of the binary Logistic regression model in prediction of placenta type and adverse clinical outcome was 91.3%.

View Presentation Video

Alessandra Maiuro^1,2, Giada Ercolani³, Maria Grazia Porpora⁴, Carlo Catalano³, Lucia Manganaro³, and Silvia Capuani^1,2
1Physics, CNR Institute for Complex Systems (ISC), Rome, Italy, ²Physics, Sapienza University of Rome, Rome, Italy, ³Radiological, Oncological and Pathological Sciences, Umberto I Hospital, Sapienza University of Rome, Rome, Italy, ⁴Maternal and Child Health and Urological Sciences, Umberto I Hospital, Sapienza University of Rome, Rome, Italy

Keywords: Placenta, Diffusion/other diffusion imaging techniques, IVIM, two-perfusion, villi, trophoblasts

The placenta may incur several pathologies during fetal growth due to perfusion impairment such as Fetal-Growth-Restriction (FGR) and the accretism. Two-perfusion IVIM model (with f₁, D₁*, f₂, D*₂ and D parameters) and IVIM model were used to fit data. DWIs were corrected for distributed noise χ. Mean-values differences of the quantified parameters in diseased and healthy placentas were analyzed by ANOVA test. The slower f₂ perfusion fraction associated with trophoblastic perfusion was significantly lower in FGR compared to normal placenta, whereas the faster f₁, quantifying villi perfusion fraction, was higher in the accretism compared to healthy placenta zone.

Qingling Song¹, Ye Li¹, and Ailian Liu^1
1Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China

Keywords: Pelvis, Cancer

Ovarian cancer is a common fatal malignant tumor in clinic, and it is also a malignant tumor in the female reproductive system, which is third common followed cervical cancer and uterine cancer. It is easy to metastasize, among which peritoneal implantation is a common way of metastasis in the early stage.

View Presentation Video

Ruiming Chen¹, Logan T. Keding^2,3, Jessica Vazquez^2,3, Kathleen Antony⁴, Heather A. Simmons^2,3, Kevin M. Johnson^1,5,6, Aleksandar K. Stanic⁴, Ruo-Yu Liu¹, Dinesh M. Shah⁴, Thaddus G. Golos^2,3,4, and Oliver Wieben^1,5,6
1Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ²Wisconsin National Primate Research Center, University of Wisconsin - Madison, Madison, WI, United States, ³Comparative Biosciences, University of Wisconsin - Madison, Madison, WI, United States, ⁴Obstetrics & Gynecology, University of Wisconsin - Madison, Madison, WI, United States, ⁵Radiology, University of Wisconsin - Madison, Madison, WI, United States, ⁶Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States

Keywords: Placenta, Quantitative Imaging

Early assessment of utero-placental vasculature is an important novel approach to predicting pregnancy outcomes and fetal growth. Ferumoxytol-enhanced MRI is a powerful tool to measure intervillous fractional blood volume (FBV) in vivo, which could reflect structural and vascular health in the placenta. This study reports such measurements for rhesus macaque placentas that underwent localized Tisseel injections to mimic the effects of local ischemia. We observed increased regions of low FBV with gestation following the Tisseel injection.

View Presentation Video

Jing Deng¹, Aining Zhang¹, Meng Zhao¹, Xihu Mu¹, Xin Zhou², Feifei Qu³, Jiacheng Song¹, and Ting Chen^1
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ²Department of Obstetrics & Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ³Department of Radiology, Siemens Healthineers Ltd, Shanghai, China

Keywords: Placenta, Perfusion

Very low birth weight infants (VLBWI) are an adverse pregnancy outcome in small for gestational age infants (SGA). We explored the value of intravoxel incoherent motion (IVIM) histogram parameters and Doppler parameters in predicting VLBWI from SGA. Compared with the SGA group, true diffusion coefficients (D_mean, D_50th, D_75th, D_90th) and perfusion fraction (f_max) were significantly lower, and umbilical artery pulsatility index, resistance index (RI), and peak systolic velocity/end-diastolic velocity were significantly higher in the VLBWI group. A combined predictive model (D_90th and RI) improved diagnostic performance and demonstrated the potential of IVIM histogram analysis for clinical diagnosis of VLBWI.

Nan Zhou¹, Weibo Chen², and Zhengyang Zhou^1
1Department of Radiology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China, ²Philips Healthcare, Shanghai, China

Keywords: Uterus, MR Value, Endometrial fibrosis; Magnetic resonance imaging; Noninvasive evaluation

Uterine morphology and endometrial T2 signal intensity can evaluate endometrial fibrosis

View Presentation Video

Ruo-Yu Liu¹, Logan T. Keding^2,3, Jessica Vazquez^2,3, Jitka Starekova⁴, Ante Zhu^4,5, Ruiming Chen¹, Kathleen M. Antony⁶, Heather A. Simmons^2,3, Aleksandar K. Stanic⁶, Diego Hernando^1,4, Dinesh M. Shah⁶, Thaddeus G. Golos^2,3,6, and Oliver Wieben^1,4,5
1Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ²Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States, ³Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ⁵Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁶Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, United States

Keywords: Placenta, Quantitative Imaging, R2* mapping

Placental R2* mapping is a non-invasive, quantitative biomarker with the potential to identify deficiency in uteroplacental oxygenation and blood flow, which would be of significant value in predicting and monitoring pregnancy complications. We introduce a novel thrombotic placental injury model and report mean values, histograms, and spatial distribution of baseline R2* at different gestational ages in healthy and ischemic rhesus macaque placenta based on blood oxygenation level dependent (BOLD) MR imaging. Higher increases in mean values and different spatial patterns of R2* are observed in placenta with induced ischemia.

Liu Ting¹, Lu Jiaojiao¹, Li Junjun¹, Hou Huilian¹, and Yang Jian^1
1First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

Keywords: Placenta, Placenta

Placenta accreta spectrum (PAS) is a serious threat to maternal life, but ultrasound and conventional MRI have limitations in the diagnosis of PAS. Intravoxel incoherent motion (IVIM) is a technique of diffusion weighted MR imaging, which allows separation of tissue diffusivity and perfusion information based on the signal intensity at varying degrees of b values. We found that IVIM was able to diagnose PAS by showing the basal plate of placenta, the structure dividing the placenta and the uterus. This new finding could improve the diagnostic efficacy of MRI in the diagnosis of PAS.

View Presentation Video

Tao Lu^1
1Sichuan Provincial People’s Hospital, Chengdu, China

Keywords: Placenta, Placenta

PAS is commonly associated with postpartum hemorrhage.DKI and IVIM were used to evaluate the placenta.The amount of bleeding during delivery was positively correlated with D, D*, f, and MD, but negatively correlated with MK.D and D* were significantly higher while MK was significantly lower in patients with PPH.A combination of placenta previa and D can be used to predict PPH in patients at high risk for PAS disorders

View Presentation Video

Quyen N. Do¹, Diane M. Twickler^1,2,3, Matthew A. Lewis¹, Christina L. Herrera^2,3, David Owen², Ananth J. Madhuranthakam^1,4, Catherine Y. Spong^2,3, Baowei Fei^1,5,6, Robert E. Lenkinski¹, and Yin Xi^1,7
1Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ²Obstetrics & Gynecology, UT Southwestern Medical Center, Dallas, TX, United States, ³Parkland Health and Hospital System, Dallas, TX, United States, ⁴Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, ⁵Center for Imaging and Surgical Innovation, UT Dallas, Richardson, TX, United States, ⁶Bioengineering and Computer Science, UT Dallas, Richardson, TX, United States, ⁷Population and Data Sciences, UT Southwestern Medical Center, Dallas, TX, United States

Keywords: Placenta, Radiomics, placenta accreta spectrum, MR images, hysterectomy

Placenta accreta spectrum (PAS) is associated with significant morbidity and mortality. We applied ROI-based radiomics analysis on axial and sagittal plane MR images in women with placenta previa and a history of previous cesarean delivery. Our goal was to compare MR textural features extracted from axial and sagittal imaging planes and compare findings to surgical outcomes. Radiomics features were significant in both anatomical planes in the MRIs of women who underwent hysterectomy.

View Presentation Video

Xiaoyi He^1,2, Hengcui Sun², Yiting Guo², Weiqiang Dou³, Dmytro Pylypenko³, Xinghua Xu¹, Dexin Yu¹, Qing Wang¹, and Fang Wang^1
1Department of Radiology, Qilu Hospital of Shandong University, Jinan, China, ²Department of Radiology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China, ³MR Research, GE Healthcare, Beijing, China

Keywords: Pelvis, Normal development

This study aimed to investigate the correlation between hiatus area and age in healthy women. 552 female subjects, divided into four groups (young, young-middle, middle, middle-elderly) based on age, were selected to underwent pelvic T2-weighted MRI for measuring hiatus area. Age showed a positive correlation with hiatus area. Also, statistically significant difference in hiatus areas was found between any two groups, except for between young-middle and middle group, and between middle and middle-elderly group. We thus proved that hiatus area of healthy women increases with age, which might serve as a reference standard in clinic.

View Presentation Video

Zhigang Wang¹, Fengleng Yang¹, Chunying Liu¹, Fang Wang¹, Ying Ying Xiong², Qiang Zhang², Meining Chen ³, and Hua Lai^1
1Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Scienc, Chengdu, China, ²Gynecology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Scienc, Chengdu, China, ³MR Scientific Marketing, Siemens Healthineers, Shanghai, China

Keywords: Urogenital, Reproductive, Cesarean Scar Pregnancy; Dynamic Magnetic Resonance Imaging; Dynamic Contrast Enhancemen; Prediction Ability; Surgical Risk

Cesarean scar pregnancy (CSP) is a rare form of ectopic pregnancy with curettage often being the first-line treatment. However, uncontrollable intraoperative hemorrhage is one of common complications during the treatment, making its prediction a critical for treatment planning. The aim of this study was to explore the feasibility of using  GRASP DCE-MRI to characterize peritrophoblastic perfusion and predict intraoperative hemorrhage for CSP. The study found that presurgical Wash-in, TTP, iAUC, Ktrans, and Ve were significantly different between hemorrhage and non-hemorrhage groups identified during curettage. The ROC-AUC analysis further demonstrated  their capability of serving as intraoperative hemorrhage predictors for CSP.

View Presentation Video

wang yilin¹, Chen yan¹, and Xu xiaojuan^1
1Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Keywords: Urogenital, MR Value, ovarian

The newly launched O-RADS scoring system was developed to address the qualitative problem of pelvic masses. However, the use of the O-RADS system in different regional populations still needs to be further verified. And the applicability of the 0-RADS scoring system for doctors of different seniority remains to be studied.

View Presentation Video

Octavia Bane^1,2, David Bennett³, Emre Altinmakas¹, Ghadi Abboud¹, Amine Geahchan¹, Jordan Cuevas^1,2, Alex Menys⁴, Ryan Ungaro⁵, Jean-Frederic Colombel⁵, and Bachir Taouli^1,2
1Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Takeda Pharmaceuticals, Cambridge, MA, United States, ⁴Motilent Ltd, London, United Kingdom, ⁵Department of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, United States

Keywords: Digestive, Quantitative Imaging, bowel, Crohn's disease

Our study aims to determine test-retest repeatability in motility (bowel wall motion) index derived from CINE-MRI measured in involved and uninvolved small bowel in patients with Crohn’s disease and in healthy volunteers, to determine a clinically significant threshold of motility change in response to treatment.Motility was lower in the involved areas compared to uninvolved small bowel, and in the uninvolved small bowel ofpatients compared to that of healthy volunteers. We found moderate test-retest repeatability in the motility index of involved bowel (provide average CV) and in the ratio ofmotility indices in involved small bowel and in uninvolved small bowel.