ISMRM & ISMRT Annual Meeting & Exhibition • 03-08 June 2023 • Toronto, ON, Canada

ISMRM & ISMRT Annual Meeting & Exhibition

Sunrise Course

When the Immune System Targets Itself: MRI for Neuroinflammation in Autoimmune Diseases

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When the Immune System Targets Itself: MRI for Neuroinflammation in Autoimmune Diseases
Sunrise Course
ORGANIZERS: Wei-Tang Chang, Audrey Fan, Xiao-Qi (Juliana) Huang
Tuesday, 06 June 2023
701A
07:00 -  08:00
Moderators: Kejia Cai & Cristina Granziera
Skill Level: Intermediate to Advanced
Session Number: S-Tu-01
CME Credit
Session Number: S-Tu-01

Overview
In this four-day Sunrise course, the role of neuroinflammation related to tumors, autoimmune diseases, neurological diseases, and psychiatric disorders will be discussed each morning with a focus on clinical cases.

Target Audience
Physicians in the related field will be introduced to new techniques and cutting-edge topics about neuroinflammation in tumors, autoimmune diseases, neurological diseases, and psychiatric disorders and how imaging can help with the relevant clinical practice.

Educational Objectives
As a result of attending this course, participants should be able to:
- Explain how to image neuroinflammation in clinical conditions with case studies;
- Describe what neuroinflammation can do on the prognosis of those conditions; and
- Explain some basic mechanism related to neuroinflammation in those conditions.
07:00 Imaging Immune-Mediated Lesions in Neuroinflammatory Diseases Cornelius Faber

Keywords: Neuro: Nervous System

Auto-immune neuroinflammatory disorders may be classified as either predominantly demyelinating, parenchymal non-demyelinating, meningeal-involving or vascular type. Similar to any type of neuroinflammation, underlying mechanisms that result in detectable lesions involve activation of resident immunocompetent cells, disruption of BBB and infiltration of peripheral immune cells. Lesions may display demyelination, edema formation, iron accumulation and atrophy, which all can be best detected using a variety of MRI sequences. Altered metabolic profiles are best observed by MR spectroscopy methods, while apoptosis/cell loss and upregulation of receptors is best detected by radioisotope-based methods, for which a wealth of tracers is available.
07:30   MRI in Autoimmune Diseases Seth Smith
 

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The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.