ISMRM23 - Cardiac & Vascular Inflammation

ISMRM & ISMRT Annual Meeting & Exhibition • 03-08 June 2023 • Toronto, ON, Canada

Cardiac & Vascular Inflammation

Weekday Course

ORGANIZERS: Christopher François, Xihai Zhao

Tuesday, 06 June 2023

701A

15:45 - 17:45

Moderators:
Vessels on Fire: Zahi Fayad
Heart on Fire: Nicole Seiberlich

Skill Level: Basic to Advanced

Session Number: Tu-06

CME Credit

Session Number: Tu-06

Overview
This clinical focus meeting session will undertake clinical and technical aspects of cardiac and vascular inflammation. The first sub-session will focus on large and medium vessel inflammation. The second sub-session will focus on cardiac inflammation. Each sub-session will include a clinical- and technique-oriented presentations.

Target Audience
Students, technologists, researchers, clinicians.

Educational Objectives
As a result of attending this course, participants should be able to:
- Describe the role of non-invasive imaging in the diagnosis and management of large and medium vessel vasculitis;
- Review the new MR techniques used for identifying and characterizing vessel wall inflammation;
- Summarize the role of cardiac MR in diagnosis and management of patients with myocardial inflammation; and
- Describe the new quantitative cardiac MR techniques used for assessing myocardial inflammation.

		Vessels on Fire
15:45		How Are MRI & PET/MRI Used in the Diagnosis & Management of Medium & Large Vessel Vasculitis? View Presentation Video Thorsten Bley Keywords: Cardiovascular: Vascular, Cross-organ: Inflammation Next to CCDS, MRI and PET are recommended imaging modalities in large vessel vasculitides. With an in-plane spatial resolution of 200x250µm2 MRI displays mural inflammatory changes (circumferential thickening, contrast enhancement) of the superficial temporal arteries in giant cell arteritis. Combined with a first pass angiography of the thoracic aorta and its branch vessels the inflammatory disease burden and vascular damage (dilatation, stenosis) can be assessed within one examination. PET is considered the most sensitive imaging modality for assessing large vessel vasculitis. Combining sensitivity of PET with anatomic information of MRI in one hybrid scan offers promising perspectives for vasculitis imaging.
16:15		New Techniques for Quantitative Assessment of Vessel Wall Inflammation View Presentation Video Chun Yuan Keywords: Image acquisition: Quantification, Cardiovascular: Atherosclerosis, Cross-organ: Inflammation Inflammation's role in vascular disease development necessitates its detection and quantification for diagnosis and risk assessment. MRI contrast agents have aided in identifying vessel wall inflammation, from atherosclerosis to vasculitis. Challenges persist in quantitatively assessing inflammation due to vascular bed differences, spatial resolution, acquisition limitations, and contrast agent properties. Recent technical advancements address these challenges, such as linking dynamic contrast enhancement to plaque inflammation, improved DCE analysis, diverse contrast media applications, and image analysis tools integrating anatomical and vascular inflammation assessments. These advancements hold clinical significance and promise for future progress in managing vascular disease.
		Heart on Fire
16:45		Role of Cardiac MR in Assessment of Myocardial Inflammation View Presentation Video Kate Hanneman Keywords: Cardiovascular: Cardiac Role of cardiac MRI in inflammation
17:15		New Techniques for Quantitative Assessment of Myocardial Inflammation View Presentation Video Claudia Prieto