ISMRM23 - Synthetic Contrasts

ISMRM & ISMRT Annual Meeting & Exhibition • 03-08 June 2023 • Toronto, ON, Canada

Synthetic Contrasts

Weekday Course

ORGANIZERS: Henrik Odéen, Yasuhiko Tachibana

Wednesday, 07 June 2023

718A

08:15 - 10:15

Moderators: Cheng-Chieh Cheng & Akifumi Hagiwara

Skill Level: Basic to Intermediate

Session Number: W-01

CME Credit

Session Number: W-01

Overview
Synthetic MRI has the potential to change the way we perform multiparametric imaging. Multiple different approaches, both for quantitative relaxometry such as T1 and T2, and for anatomy-specific contrasts such as FLAIR and MPRAGE for neuro applications, have been described in the literature. These include methods such as multi-pathway multi-echo acquisition, syMRI, MR multitasking, MR fingerprinting, MAGIC, NeuroMix, etc. This session will first provide an introduction to what methods and approaches are currently available in the clinic with examples of applications, and then go into depth on more advanced neuro and body applications in the research setting.

Target Audience
Scientists and clinicians not familiar with synthetic MRI who want to have an understanding of currently available clinical techniques and applications, as well as scientists and clinicians who want to learn about cutting-edge techniques in neuro and body applications.

Educational Objectives
As a result of attending this course, participants should be able to:
- Summarize the technical methods and applications currently available in the clinic;
- Identify opportunities and challenges with applications of these techniques in the brain; and
- Identify opportunities and challenges with applications of these techniques outside the brain.

08:15		Synthetic contrast: technical aspect and recent advancement View Presentation Video Fuyixue Wang Keywords: Image acquisition: Multiparametric, Image acquisition: Image processing, Image acquisition: Fast imaging Synthetic images with flexibly adjustable contrasts can be generated from quantitative multi-parametric MRI. With the advancement of fast multi-parametric imaging, synthetic imaging provides a more efficient MR exam paradigm to obtain clinically useful contrasts. This talk will cover the technical aspect of synthetic imaging. It will present the i) basics of contrast synthesis; 2) fast quantitative multi-parametric acquisition and their recent advancement, including multidynamic multiecho (MDME), MR Fingerprinting (MRF), MR Multitasking, and Echo-Planar Time-resolved Imaging (EPTI); and 3) recent advancement of imaging synthesis methods including machine learning based approaches. We will also discuss the future directions of synthetic imaging.
08:45		Synthetic contrast in the clinic - applications View Presentation Video Shohei Fujita Keywords: Contrast mechanisms: Relaxometry This lecture will provide a brief introduction to synthetic imaging techniques and explore the various clinical applications that highlight the advantages of these techniques in patient care and diagnosis. Both the potential benefits and drawbacks of synthetic imaging techniques will be discussed.
09:15		Advanced synthetic contrasts - brain View Presentation Video Bruno Madore Keywords: Image acquisition: Quantification Exams that are shorter in time and more quantitative in nature may represent the future of MRI. If physical parameters such as T1 and T2 can be rapidly quantified, then one can just calculate (rather than acquire) the desired images. New or cutting-edge quantitative and synthetic imaging methods often tend to be first developed for neuroimaging, because brain imaging represents such an important share of clinical MRI and because motion problems tend to be somewhat manageable when imaging the head. This talk aims to present an up-to-date description of the synthetic and quantitative imaging field, along with current associated challenges.
09:45		Advanced synthetic contrasts - MSK View Presentation Video Jan Fritz