ISMRM24 - All About Head & Neck: Imaging Brain Microstructure

All About Head & Neck: Imaging Brain Microstructure

Sunrise Course

ORGANIZERS: Wei-Tang Chang, Seena Dehkharghani, Xiao-Qi (Juliana) Huang

Wednesday, 08 May 2024

Room 331-332

07:00 - 08:00

Moderators: Yingxue Gao & Lirong Yan

Skill Level: Intermediate to Advanced

Session Number: S-W-06

CME Credit

Session Number: S-W-06

Overview
This four-day morning courses cover topics from acute ischemic stroke diagnosis to head and neck cancer imaging. The curriculum blends theoretical and practical insights on topics like clot characterization, cerebrovascular MR biomarkers, brain microstructure and MRI in neuropsychiatric disorders. The course aims to empower the participants with the expertise for informed diagnostics and treatment.

Target Audience
Clinicians, radiologists and MR researchers who wish to have in-depth understanding in head and neck MRI

Educational Objectives
As a result of attending this course, participants should be able to:
- Identify MRI techniques for diagnosing and managing head and neck conditions;
- Describe and identify MR biomarkers and imaging approaches applicable to cerebrovascular and oncological diseases; and
- Describe MRI methods for quantifying brain microstructure.

07:00		Imaging Brain Microstructure in Neuropsychiatric Disorders View Presentation Video Ileana Jelescu
07:30		Imaging Brain Microstructure with Diffusion-Based Techniques View Presentation Video Els Fieremans Keywords: Contrast mechanisms: Microstructure, Neuro: White matter, Neuro: Grey matter This lecture will present the state-of-the art of brain microstructure mapping by biophysical modeling of diffusion MRI (dMRI). At long diffusion times, axons can be modeled as impermeable sticks, leading to the so-called standard model (SM) unifying popular WM models including NODDI, WMTI and SMT. We will discuss how to improve estimation of SM and free water fraction by acquiring complimentary information (high diffusion weighting, free gradient waveforms, varying echo-times). Next, we will also discuss how to measure microstructural features beyond the standard model in white matter (axon diameters and axonal beading) and gray matter (soma density and exchange).