| Tumor
MR Spectroscopy and Imaging – Models Hall C |
| W 1342. Altered Glucose Handling is an Early Event in Apoptosis, N.R. Maisey, T.A.D. Smith, M.O. Leach and S.M. Ronen, Royal Marsden Hospital, Sutton, Surrey, UK. |
| Th 1343. Multinuclear NMR Studies of Apoptotic Changes in a Human Tumour Cell Line During Miltefosine Treatment. J. Henke, U. Flögel, J. Pfeuffer and D. Leibfritz, University of Bremen, Bremen, Germany. |
| M 1344. Gonadotropin Regulation of Adhesion in MLS Human Ovarian Cancer Cells, Y.S. Schiffenbauer, R.B. Shavit and M. Neeman, The Weizmann Institute of Science, Rehovot, Israel and Hadassah-University Hospital, Jerusalem, Israel. |
| T 1345. Metabolic Boyden Chamber Detects Significant Differences in Invasion for Metastatic and Nonmetastatic Prostate Cancer Cells, U. Pilatus, E.A. Ackerstaff, D. Artemov, N. Mori, R.J. Gillies and Z.M. Bhujwalla, The Johns Hopkins University School of Medicine, Baltimore, MD, USA and University of Arizona, Tucson, AZ, USA. |
| W 1346. Herpes Simplex Virus (HSV-1) Mediated Viral Therapy of Murine Brain Tumors Monitored by MRI, H. Poptani, C.G. Miller, N.W. Fraser and J.D. Glickson, University of Pennsylvania, Philadelphia, PA, USA. |
| Th 1347. 19F-MRS Studies of the Novel Thymidylate Synthase (TS) Inhibitor, ZD9331, P.M.J. McSheehy, A.S.E. Ojugo, M.O. Leach, I.R. Judson and J.R. Griffiths, St. George's Hospital Medical School, London, UK and Institute of Cancer Research, Sutton, Surrey, UK. |
| M 1348. Accumulation of Phosphocholine in MCF7 Human Breast Cancer; The Role of Choline Transport and Phosphorylation, R. Katz-Brull, R. Margalit, P. Bendel and H. Degani, Weizmann Institute of Science, Rehovot, Israel. |
| T 1349. In Vivo TQF 23Na MRS of Morris Hepatoma 7777 Using TmDOTP5-, P.M. Winter, H. Poptani, J.D. Glickson and N. Bansal, University of Pennsylvania, Philadelphia, PA, USA. |
| W 1350. Uptake and Washout of Borocaptate Sodium (BSH) and Borono-Phenylalanine (BPA) in Melanoma Cells: an in-vitro Multinuclear NMR Study, V. Panov, Y. Salomon, G.W. Kabalka and P. Bendel, The Weizmann Institute of Science, Rehovot, Israel and University of Tennessee, Knoxville, TN, USA. |
| Th 1351. FDG (2'-Fluoro-2'-Deoxyglucose) Tumor Metabolism Detected by 19F-MRS in vivo Correlates with Therapeutic Response, P.M.J. McSheehy, M.O. Leach, I.R. Judson and J.R. Griffiths, St. George's Hospital Medical School, London, UK and Institute of Cancer Research, Sutton, Surrey, UK. |
| M 1352. Fluorine-19 NMR Imaging of the Biodistribution and Metabolization of the Antienoplastic Agent Gemcitabine in Tumor-Bearing Rats, M.E. Bellemann, U. Haberkorn, L. Gerlach, J. Blatter and G. Brix, German Cancer Research Center, Heidelberg, Germany and Lilly Deutschland GmbH, Bad Homburg, Germany. |
| T 1353. Biodistribution and Pharmacokinetics of the Radiosensitizer 3-Aminobenzamide: Assessment with Fluorine-19 NMR Imaging, M.E. Bellemann, A. Schlicker, W. Mier, P. Peschke and G. Brix, German Cancer Research Center, Heidelberg, Germany and University of Applied Sciences, Jena, Germany. |
| W 1354. Investigations of Modulation of 5-Fluorouracil (FU) Pharmacokinetics by 5-Ethyl-2'Deoxyuridine (EUdR) in Tumor-Bearing Mice and Rats, P.M.J. McSheehy, J. Kralovánsky, A. Jeney, E. Pandi, C. Katona, P. Noordhuis, G.F. Peters, L.M. Rodrigues and J.R. Griffiths, St. George's Hospital Medical School, London, UK; Institutes of Oncology and Pathology, Budapest, Hungary and Free University, Amsterdam, The Netherlands. |
| Th 1355. Biochemical Modulation of the Anticancer Drug 5-Fluorouracil by Bromovinyluracil: Assessment with Metabolic 19F MR Imaging, G. Brix, M.E. Bellemann, L. Gerlach and U. Haberkorn, Federal Office for Radiation Protection, Neuherberg, Germany and German Cancer Research Center, Heidelberg, Germany. |
| M 1356. 1H MRS of Cell Extracts Can Monitor the Effects on Cell Metabolism Due to Growth Impairment in Gamma Irradiated HeLa Cells, S. Grande, A.M. Luciani, A. Rosi, V. Viti and L. Guidoni, Istituto Superiore di Sanita, Rome, Italy. |
| T 1357. Metabolic Effects of an IFN-g/TNF-a Combination Therapy on HT-29 Cells as Determined by High-Resolution 31P and 1H NMR Spectroscopy of PCA Extracts, N.W. Lutz and P.J. Cozzone, Faculté de Médecine, Marseille, France. |
| W 1358. Effect of 6-Aminonicotinamide on Human Tumor Metabolism, and Response to Chemotherapy and Radiation, A. Holleran, Y. Chen and J.A. Koutcher, US Patent Office and Memorial Sloan Kettering Cancer Center, New York, NY, USA. |
| Th 1359. Characterization of Lactate Levels in Normal and Malignant Human Mammary Epithelial Cells, E.O. Aboagye and Z.M. Bhujwalla, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. |
| M 1360. Measurements of Lactate Turnover in Rat Intracerebral C6 and 9L Gliomas Using 1H{13C} MRS, M. Terpstra, M. Mescher and M. Garwood, University of Minnesota Medical School, Minneapolis, MN, USA. |
| T 1361. Tumour Selective in Vivo 13C-CP NMR Assessment of Glycolytic Rate Under Various Oxygenation States, F.U. Nielsen, M.R. Horsman, P. Daugaard, H. Stødkilde-Jørgensen and R.J. Maxwell, Aarhus University, Denmark and Mount Vernon Hospital, Northwood, UK. |
| W 1362. Glucose Metabolism in MCF7 Breast Cancer; In Vivo 13C MRS Studies, D. Rivenzon-Segal, R. Margalit, P. Bendel and H. Degani, Weizmann Institute of Science, Rehovot, Israel. |
| Th 1363. Detection and Assignment of Phosphocreatine Signal in vivo in 1H NMR Spectra at 9.4 Tesla, J. Pfeuffer, I. Tkac, K. Ugurbil, M. Garwood and R. Gruetter, University of Minnesota Medical School, Minneapolis, MN, USA. |
| M 1364. Effects of Bafilomycin A1 on Tumor pH, Metabolism and Growth, P.M.J. McSheehy, C. Box, L. Kelly, L. Kelland, M.O. Leach, I.R. Judson and J.R. Griffiths, George's Hospital Medical School, London, UK and Institute of Cancer Research, Sutton, Surrey, UK. |
| T 1365. Towards a quantitative understanding of tumor pH and metabolism, P.A. Schornack, T.W. Secomb and R.J. Gillies, University of Arizona, Tucson, AZ, USA. |
| W 1366. Does Lactate Distribution Across the Cell Membrane Reflect the Transmembrane pH in Tumour and Normal Tissue? M. Stubbs, S.P. Robinson, C.A. Parkins and J.R. Griffiths, St. George's Hospital Medical School, London, UK and Mount Vernon Hospital, Northwood, Middlesex, UK. |
| Th 1367. pH Heterogeneity in Spheroids by 1H MRSI Microscopy, J. Alvarez-Pérez, R. van Sluis, N. Raghunand, Z. Bhujwala, S. Cerdán, R.J. Gillies and P. Ballesteros, C.S.I.C., Madrid, Spain; University of Arizona, Tucson, AZ, USA; John Hopkins University, Baltimore, MD, USA and UNED, Madrid, Spain. |
| M 1368. 31P MRS Measurements of Tumor pH in Mice Subjected to Acute Metabaolic Alkalosis, N. Raghunand, B. Mahoney, R. van Sluis, B. Baggett and R.J. Gillies, University of Arizona Health Sciences Center, Tucson, AZ, USA. |
| T 1369. Intravenous Administration of Perfluorocarbons Overestimates Tumor Oxygen Tension in the GH3 Xenograft, D.J.O. McIntyre, C.L. McCoy, S.P. Robinson, D.R. Collingridge and J.R. Griffiths, St. George's Hospital Medical School, London, UK and Yale University School of Medicine, New Haven, CT, USA. |
| W 1370. Changes in Tumor Oxygenation/Perfusion Monitored by Gradient Echo Imaging, L. Nadal, H. Poptani, J.E. Biaglow and J.D. Glickson, University of Pennsylvania, Philadelphia, PA, USA. |
| Th 1371. Correlation of Proton and Fluorine-19 MR Measurements of Tumor Oxygenation, H.A. Al-Hallaq, M. Zamora and G.S. Karczmar, University of Chicago, Chicago, IL, USA. |
| M 1372. Effects of Different Levels of Hypercapnic Hyperoxia on Tumour GRE MR Image Intensity and Arterial Blood Gases, S.P. Robinson, L.M. Rodrigues, M. Stubbs and J.R. Griffiths, St. George's Hospital Medical School, London, UK. |
| T 1373. Dynamic Diffusion Weighted MRI to Monitor Ca2+ Channel Blocker-Induced Changes in Tumor Microcirculation, M. Muruganandham, N.R. Jagannathan, P.C. Jain and V. Jain, University of Delhi, Delhi, India and All India Institute of Medical Sciences, New Delhi, India. |
| W 1374. Dynamic Contrast-Enhanced MRI to Monitor Perfusion and Permeability Changes in Human Tumours during Treatment by the Vascular Targeting Agent DMXAA, S.M. Galbraith, N.J. Taylor, J.J. Stirling, G. Rustin and H. Baddeley, Mount Vernon Hospital, Northwood, Middlesex, UK. |
| Th 1375. Imaging Blood Flow in Brain Tumors Using Arterial Spin Labeling, A.C. Silva, S-G. Kim and M. Garwood, University of Minnesota Medical School, Minneapolis, MN, USA. |
| M 1376. Diffusion Compartmentation in Multicellular Tumor Spheroids, E. Smouha and M. Neeman, Weizmann Institute of Science, Rehovot, Israel. |
| T 1377. Histologic Characterization of Tumor Heterogeneity by Diffusion MRI; Mapping the Extracellular Volume Fraction at High Spatial Resolution, Y. Paran, R. Edgar, P. Bendel and H. Degani, Weizmann Institute of Science, Rehovot, Israel. |
| W 1378. Return-to-the-Origin Probability and ADC Mapping as Indicators of Efficacy of Chemotherapy in RIF-1 Tumors, M.R. Meiler, K.G. Helmer and C.H. Sotak, Worcester Polytechnic Institute and University of Massachusetts Medical School, Worcester, MA, USA. |
| Th 1379. Comparison of the Return-to-the-Origin Probability and Apparent Diffusion Coefficient of Water to Map Murine Tumor Necrosis, M.R. Meiler, K.G. Helmer and C.H. Sotak, Worcester Polytechnic Institute and University of Massachusetts Medical School, Worcester, MA, USA. |
| M 1380. Comparison Between MR Diffusion Imaging and Pathological Findings of the VX2 Carcinoma in Rabbits after Ethanol Injection, M. Kuginuki, M. Matoba, Y. Kuginuki, H. Yokota, H. Tonami and I. Yamamoto, Kanazawa Medical University, Ishikawa, Japan. |
| T 1381. Increases in Water Mobility Detected by MR Diffusion Mapping Predict Treatment Responses in Experimental Brain Tumors Follow Chemo- and Gene Therapy, T.L. Chenevert, L.D. Stegman, A. Rehemtulla and B.D. Ross, University of Michigan, Ann Arbor, MI, USA. |
| W 1382. In Vivo Measurements of Size of Lipid Droplets in C6 Rat Glioma: 1H Diffusion Measurements, H. Lahrech, C. Remy, R. Farion, S. Zoula and M. Decorps, Hôpital A. Michallon, Grenoble, France. |
| Th 1383. Inhibition of Tetraphenylphosphonium-induced NMR-visible Lipid Accumulation by Chlorpromazine, N. Sathasivam, S. Brammah, L.C. Wright and E.J. Delikatny, University of Sydney and Concord Hospital, Sydney, NSW, Australia. |
| M 1384. Mobile Lipid (ML) Production in C6 Perfused Cells: Effect of Confluence and Acid pH Stress, I. Barba, P. Mann, M. Cabañas, C. Arús and C. Gasparovic, Universitat Autònoma de Barcelona, Spain and University of New Mexico, Albuquerque, NM, USA. |
| T 1385. 1H-NMR Spectroscopic Study of Lipid Signals in Sensitive, Drug-Resistant and Revertant K562 Cells: T1 Measurements and Subcellular Localization by Nile Red Staining, P. Legouin, L. Le Moyec, M. Kawakami, D. Briane, B. Collet, G. Leray and J.D. de Certaines, Université de Rennes l, Rennes, France; CSSB-UFR SMBH, Bobigny, France and Centre Régional de lutte contre le cancer, Rennes, France. |
| W 1386. NMR Imaging of the Development of Hepatic Tumours in an Animal Model, L.M. Foley, R.A. Towner, P. Russell and D.M. Painter, James Cook University, Townsville, Queensland, Australia and Royal Prince Alfred Hospital, Sydney, NSW, Australia. |
| Th 1387. Mapping White Matter Tracts Involved with the Dissemination of Primary Brain Tumors: A Preliminary Investigation in Rats Using Intracerebral Albumin-(Gd-DTPA) with MRI, J. Portnow, D. Artemov, S. Eller, M. Solaiyappan, S.A. Grossman and Z. Bhujwalla, Johns Hopkins University, Baltimore, MD, USA. |