MR Spectroscopy of White Matter Disease and Degeneration

Hall C
Monday: 14:00 – 16:00
Tuesday – Thursday: 13:30 – 15:30
W 1434. Donepezil's Effect on N-Acetyl Aspartate Levels of Alzheimer's Patients using Proton Magnetic Resonance Spectroscopy, X. Yu, K.R.R. Krishnan, J. Mintzer, R. Weisler, C. Perdomo, R. Pratt, J. Ieni and H.C. Charles, Duke University, Durham, NC, USA; Medical University of South Carolina, Charleston, SC, USA and Eisai Inc., Teaneck, NJ, USA.
Th 1435. Dementia Syndrome: Correlation of Biochemical Markers as Assessed by 1H-MR Spectroscopy with the Severity of Dementia, C. Gorriz, S. Herminghaus, U. Pilatus, L. Frölich, J. Wittsack, T. Dierks, W. Möller-Hartmann, K. Maurer, H. Lanfermann and F.E. Zanella, University of Frankfurt, Frankfurt, Germany.
M 1436. Difference Between Slowly Progressive Aphasia without Generalized Dementia and Alzheimer's Disease by Proton Chemical Shift Imaging, O. Kizu, S. Naruse, S. Furuya, K. Yamada, M. Ikejiri and T. Maeda, Kyoto Prefectural University of Medicine, Kyoto, Japan.
T 1437. Regional Pattern of Diminished Levels of Cortical NAA in Alzheimer's Disease and Vascular Dementia, N. Schuff, A.A. Capizzano, D. Amend, A. Gamst, W. Jagust, G. Fein, A.A. Maudsley and M.W. Weiner, DVA Medical Center and University of California, San Francisco, CA, USA; University of California, San Diego, CA, USA and Lawrence Berkeley Laboratories, Berkeley, CA, USA.
W 1438. Decreased Cortical NAA in Subcortical Ischemic Vascular Dementia, A.A. Capizzano, N.W. Schuff, D.L. Amend, J.L. Tanabe, D. Norman, A.A. Maudsley, W. Jagust, H. Chui, G. Fein and M.W. Weiner, VA Medical Center and University of California, San Francisco, CA, USA.
Th 1439. Influence of Partial Volume Effect on Metabolite Concentrations in Multiple Sclerosis Lesions Estimated from Localized Proton MR Spectra, L. Stawiarz, G. Helms, P. Kivisäkk, S. Fredrikson, J. Hillert and H. Link, Huddinge University Hospital, Huddinge, Sweden and Karolinska Hospital, Stockholm, Sweden.
M 1440. Creatine and Myo-Inositol are Increased in Multiple Sclerosis Normal Appearing White Matter, M. Vermathen, W.D. Rooney, D.E. Goodkin and M.W. Weiner, DVA Medical Center and University of California, San Francisco, CA, USA and Brookhaven National Laboratory, Upton, NY, USA.
T 1441. Quantitation of Total Brain NAA Decline and Atrophy with Disease Duration in
Relapsing-Remitting MS, Y. Ge, O. Gonen, J.S. Babb, L.J. Mannon, D. Kolson, J.K. Udupa and R.I. Grossman, University of Pennsylvania Medical Center and Fox Chase Cancer Center, Philadelphia, PA, USA.
W 1442. T2 Measurement, Magnetisation Transfer and Segmentation of Extra- and Intracellular Volumes on Discrete "Black Hole" Multiple Sclerosis Lesions, G. Helms, L. Stawiarz and H. Link, Karolinska Institutet, Stockholm, Sweden.
Th 1443. Comparison of Primary Progressive and Relapsing Remitting Multiple Sclerosis by 1H MRSI, J. Suhy, W.D. Rooney, D.E. Goodkin, A.A. Capizzano, A.A. Maudsley and M.W. Weiner, University of California San Francisco and DVA Medical Center, San Francisco, CA, USA and Brookhaven National Laboratory, Upton, NY, USA.
M 1444. Quantitating Total Brain NAA and Its Decline with Age in Multiple Sclerosis Using Non-Echo
1H MRS, O. Gonen, I. Catalaa, S.V. Swaminathan, J.S. Babb, L.J. Mannon, D. Kolson and R.I. Grossman, Fox Chase Cancer Center and University of Pennsylvania Medical Center, Philadelphia, PA, USA.
T 1445. Depletion of Glutamate in the Motor Cortex in Huntington's Disease Measured using Short Echo STEAM at 3 Tesla, C.C. Hanstock, R.B. Thompson, M. Wieler, P.S. Allen and W.R.W. Martin, University of Alberta, Edmonton, Alberta, Canada.
W 1446. Metabolic Concentration of Basal Ganglia in Patients with Schizophrenia by in vivo Proton MRS, T. Fujimoto, T. Matsumoto, T. Nakano, T. Takano, K. Takeuchi, M. Nakashima, Y. Atsuji, K. Kiue, T. Nakano,
K. Nakamura and H. Akimoto, South Japan Health Science Centre, Fujimoto Hospital, Miyakonojo, Japan.
Th 1447. Brain Proton Magnetic Resonance Spectroscopy of Patients with the Sjögren-Larsson Syndrome, A. Heerschap, M. Willemsen, P. van Domburg, H. Thijssen, J. De Jong, F. Gabreëls and J. Rotteveel, University Hospital Nijmegen, Nijmegen, The Netherlands.
M 1448. Magnetization Transfer Attenuation of Creatine Resonances in Localized Proton MRS of Human Brain, G. Helms and J. Frahm, Biomedizinische NMR Forschungs GmbH, Göttingen, Germany.
T 1449. 1H-MR Spectroscopy in Myotonic Dystrophy, Y. Koshimoto, H. Kimura, M. Maeda, H. Yamada, Y. Kawamura and Y. Ishii, Fukui Medical University, Fukui, Japan.
W 1450. 31P Chemical Shift Imaging in Patients with Schizophrenia, T. Fujimoto, T. Matsumoto, T. Yamamoto, T. Takano, K. Takeuchi, K. Nakamura, T. Uchida and H. Akimoto, Fujimoto Hospital, Miyakonojo, Japan and Hokkaido University, Hokkaido, Japan.
Th 1451. An MR Study of Lesion Heterogeneity in Patients with Secondary Progressive MS: Correlation between Metabolic Concentration, T1 Relaxation Time and Appearance on T1-Weighted MRI, P.A. Brex, S.M. Leary, G.J.M. Parker, P.D. Molyneux, C.A. Davie, A.J. Thompson and D.H. Miller, University College London, London, UK.
M 1452. Competitive Blood-Brain-Barrier Dynamics Observed by 1H MR Spectroscopy and EEG in Patients with Phenylketonuria, R. Kreis, J. Pietz, J. Slotboom, A. Rupp, E. Mayatepek, D. Rating, H.J. Bremer and C. Boesch, University Bern, Switzerland and University Heidelberg, Germany.
T 1453. 1H MR Spectroscopy and Quantitative Cerebropetal Blood Flowmetry in Idiopathic Anatomic Megalencephaly, K.P.J. Braun, J. van der Grond and R.H.J.M. Gooskens, University Hospital, Utrecht, The Netherlands.
W 1454. Proton MRS and Neuropsychological Assessments in the AIDS Dementia Complex:
A Multi-Center Study, P.L. Lee, C. Yiannoutsos, L. Chang, T. Ernst, E. Miller, D. Kolson, R.R. Lenkinski, B.A. Navia and R.G. Gonzalez, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA; Harvard School of Public Health, Boston, MA, USA; Harbor-UCLA Medical Center, Torrance, CA, USA; University of Pennsylvania, Philadelphia, PA, USA and New England Medical Center, Boston, MA, USA.
Th 1455. 1H-MRS is a Functional Measure: A Study of Cognition in Systemic Lupus Erythematosus, W.M. Brooks, R.E. Jung, C.A. Stidley, R.A. Yeo and W.L. Sibbitt Jr., University of New Mexico, Albuquerque, NM, USA.
M 1456. The Contribution of Magnetic Resonance to Explaining Phenylketonuria Brain Lesions, M. Dezortová, M. Hájek, J. Tintìra, L. Hejcmanová and E. Syková, Institute for Clinical and Experimental Medicine, Third Medical Faculty and Second Medical Faculty UK and Institute for Experimental Medicine, ASCR, Prague, Czech Republic.
T 1457. Self-Organizing Neural Network for Pattern Recognition of Short Echo Time 1H NMR Brain Spectra, E. Cabanes, S. Confort-Gouny, Y. Le Fur, A.M. Salvan, J. Vion-Dury and P.J. Cozzone, Faculté de Médecine de Marseille, France.
W 1458. Short-Echo Time Localized 1H Spectroscopy of the Brain for Follow-Up Examination of Hepatic Encephalopathy after Transjugular Intrahepatic Portosystemic Shunting (TIPS), T. Nägele, U. Seeger, P. Pereira, I. Mader, M. Eisold, U. Klose, F. Schick, S. Miller, W. Grodd and K. Voigt, University of Tübingen, Germany.
Th 1459. Short Echo Proton MR Spectroscopy of Macromolecules in White Matter Disease, I. Mader, U. Seeger, R. Weisert, U. Klose, T. Naegele and W. Grodd, Eberhard-Karls-University, Tuebingen, Germany.
M 1460. Clinical Utility of 3D Proton Magnetic Resonance Spectroscopic Imaging (3D-MRSI) Using Short-TE PRESS in AIDS Patients; Evaluation of Simple Method for Semi-Quantitative Analysis of Cerebral Metabolites, K. Yoshikawa, Y. Inoue, S. Asai, Y. Hoshino, A. Iwamoto, T. Ogino, M. Umeda and T. Matsuda, University of Tokyo and National Institute of Neuroscience, Tokyo, Japan; College of Oriental Medicine, Kyoto, Japan and GE Yokogawa Medical Systems, Ltd., Tokyo, Japan.
T 1461. Brain Metabolic Alterations in Cushing's Syndrome as Monitored by Proton Magnetic Resonance Spectroscopy, A. Khiat, C. Bard, A. Lacroix, J. Rousseau and Y. Boulanger, CHUM, Montréal, Québec, Canada.

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