Quiz: MSK – Whole Body MRI for Musculoskeletal Oncology – Anwar Padhani

Which of the following imaging modalities would be best used to image the cell density of prostate metastases?

FDG PET
Whole body bone scintigraphy
DWI with ADC mapping
PMSA
MR Spectroscopy

Jump to the relevant part of the video for the above question:

For metastatic disease that is characterized by low glucose metabolism, which of the following whole body techniques would be most useful for follow-up imaging after treatment?

FDG PET
Whole body bone scintigraphy
Whole body DWI with ADC mapping
Whole body CT

Jump to the relevant part of the video for the above question:

Regarding a bone metastasis with a “ring” or “halo” appearance on STIR, which of the following statements is true?

The ring represents the hypercellular portion of the lesion which is typically the osteolytic site of expansion.
The ring represents the zone of perilesional reactive sclerosis associated with the metastasis.
The center of the ring is typically a lytic lesion where osteoclastic activity predominates.
The ring signified cell death.

Jump to the relevant part of the video for the above question:

Which of the following features most suggests treatment response and cell death in a tumor following treatment, compared to its imaging appearance prior to treatment?

An increase in signal on the b800 DWI sequence
An ADC histogram shift to the right
A decrease in T1 signal
An increase in STIR signal
A simultaneous decrease in STIR and increase in b800 DWI signal

Jump to the relevant part of the video for the above question:

Which of the following is true about treatment response?

When there is good treatment response in the bone marrow, other sites of disease almost always also exhibit good response.
An ADC histogram shift to the right heralds a poor treatment response in the bone marrow.
With treatment response, the bone marrow shows predictable changes by T1 and STIR.
Metastatic bone marrow disease may respond heterogeneously, with areas of progression and pseudo-progression.

Jump to the relevant part of the video for the above question: