Quiz: Neuro: Pediatrics: Acquired Pediatric CNS Disorders 3

Which of the following is true regarding pediatric demyelinating diseases?

ADEM can never be multiphasic or recurrent
Multiple sclerosis lesions in children have very little in terms of overlapping imaging features compared to similar lesions in adults
Encephalopathy is a key feature of ADEM
Features of ADEM and multiple sclerosis (MS) initial presentation in children can never overlap
Periventricular lesions and T1 hypointense lesions are more typical of ADEM than MS

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Features of NMO (neuromyelitis optica) include which of the following:

Optic neuritis
Transverse myelitis extending longer than 3 vertebral height segments
NMO IgG seropositivity
Involvement of the area postrema, periventricular region adjacent to 3rd ventricle
All of the above.

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Which of the following is most characteristic of acute necrotizing encephalitis (ANE) and distinguishes it from ADEM?

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