Quiz: Neuro: Pediatrics: Acquired Pediatric CNS Disorders 4

Leigh Syndrome can commonly produce bilateral symmetric T2 hyperintensities in which regions?

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Lactate peaks can be seen in proton MR spectroscopy in which of the following inborn errors of metabolism?

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Which of the following statements is true?

a. MELAS tends to affect both cortex and deep gray matter
b. Leigh Syndrome tends to affect primary deep gray matter
c. Both of the above tend to be associated with T2 hyperintensity in the basal ganglia, whereas NBIA/PKAN is associated with low T2 signal in globus pallidus peripherally (“eye of the tiger” appearance)
a, b and c
None of the above

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