ISMRM Workshop on
MR Spectroscopy:
Frontiers in Molecular & Metabolic Imaging
calendar_month
15-18 October 2024
location_on
Mass General Brigham Assembly Row
Boston, MA, USA
Organizers
Co-Chairs:
Ovidiu C. Andronesi, M.D., Ph.D.
Chao Ma, Ph.D.
Call for Abstracts & Stipend Applications
Abstract submission deadline:
Declarations & Supporters
Faculty declarations will be available approximately two weeks before the workshop begins.
For Presenters & Attendees
Program Options:
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Overview & Program
Workshop Overview
Magnetic resonance spectroscopy (MRS) can simultaneously image up to 20 metabolites in the brain and assess their concentration and the dynamic change of their concentrations under functional tasks. MRS is capable of measuring intrinsic metabolism non-invasively without the need of contrast agents and can probe metabolic enzymatic rates that are not accessible by other imaging techniques. Numerous studies have demonstrated the considerable value of MRS for clinical applications. Great progress has been realized over the last few years in the performance of MRS resulting in fast and high-resolution imaging methods with robust performance in clinical and research investigations.
The ability to probe metabolic alterations is important to understand disease mechanisms and for patient management, including diagnosis, treatment planning, and treatment response assessment. In addition, MRS allows to probe metabolism in healthy individuals and in healthy tissues of patients providing important information about normal function.
This workshop will present the state of the art in technical performance and clinical applications of MRS, which will be relevant to a broad audience of scientists and clinicians. In particular, the topics of interest include: the fundamentals of MRS methodology; biological and clinical relevance of metabolism; advanced MRS methodology; and clinical and pre-clinical applications in healthy conditions and diseases such as cancer, neuropsychiatric disorders, and inborn errors of metabolism. Practical sessions of MRS imaging protocols and data analysis will be demonstrated during this workshop as well.
The program will combine lecture sessions provided by experts in the field and abstract sessions to present the work of attendees. This meeting will provide a forum to share best practices, disseminate knowledge and methodology, and create consensus and standardization through panel discussions and practical demonstrations.
Target Audience
Scientists and clinicians interested in learning the state of the art of in-vivo MRS to image metabolism under healthy and disease conditions.
Educational Objectives
Upon completion of this activity, participants should be able to:
Preliminary Program
Day 1 - Tuesday, 15 October 2024
07:30
Registration & Speaker Upload Available
Session 1: Basics of MRS(I) Part I: Acquisition & Reconstruction
Moderators: T.B.A.
08:00
Opening Statements
T.B.A.
08:30
Metabolism & MRS
T.B.A.
08:50
MRS Data Acquisition
T.B.A.
09:10
MRS Data Processing
T.B.A.
09:30
Spectral Fitting & Quantification
T.B.A.
09:50
Standardization
T.B.A.
10:10
Break & Speaker Upload Available
10:40
Proffered Papers - Oral Session
11:40
Keynote Address: MRS Historical Perspective
T.B.A.
12:20
Lunch & Speaker Upload Available
Poster Viewing
13:30
Poster Session
Session 2: Basics of MRS(I) Part II: Auxiliary Techniques
Moderators: T.B.A.
14:00
B0 Shimming
T.B.A.
14:20
Motion Correction
T.B.A.
14:40
Water & Lipid Suppression
T.B.A.
15:00
Spectral Editing & 2D MRS
T.B.A.
15:20
Functional & Diffusion-Weighted MRS
T.B.A.
15:40
Break & Speaker Upload Available
Session 3: Preclinical MRS
Moderators: T.B.A.
16:10
Experimental Techniques for Preclinical MRS
T.B.A.
16:30
Targeted Metabolomics
T.B.A.
16:50
Metabolic Flux by MRS
T.B.A.
17:10
Pharmacological MRS
T.B.A.
17:30
Consensus on Preclinical MRS
T.B.A.
18:00
Proffered Papers - Oral Session
18:50
Adjourn
Day 2 - Wednesday 16 October 2024
07:30
Registration & Speaker Upload Available
Session 4: Advanced MRSI
Moderators: T.B.A.
08:30
Spectral-Spatial Encoding
T.B.A.
08:50
Undersampling Techniques
T.B.A.
09:10
Ultra-High Field MRSI
T.B.A.
09:30
Special Hardware for MRSI
T.B.A.
09:50
Deep Learning in MRSI
T.B.A.
10:10
Proffered Papers - Oral Session
10:40
Break & Speaker Upload Available
11:40
Keynote Address: MRS(i) State-of-the-Art/New Horizons
T.B.A.
12:20
Lunch & Speaker Upload Available
Poster Viewing
13:30
Poster Session
Session 5: X-Nuclei & Hyperpolarized MRS/MRSI
Moderators: T.B.A.
14:00
31P MRS/MRSI
T.B.A.
14:20
Deuterium Imaging
T.B.A.
14:40
13C MRS/MRSI
T.B.A.
15:00
Hyperpolarized 13C Imaging
T.B.A.
15:20
Spectroscopy in the Millitesla Regime & Non-DNP Hyperpolarization
T.B.A.
15:40
Proffered Papers - Oral Session
16:10
Break & Speaker Upload Available
17:00
Industry/Sponsor Presentations (No CME Available)
18:00
Adjourn
Day 3 - Thursday, 17 October 2024
07:30
Registration & Speaker Upload Available
Session 6: Clinical Applications of MRS
Moderators: T.B.A.
08:30
MRS of Cancer
T.B.A.
08:50
MRS in Neuropsychiatric Diseases
T.B.A.
09:10
MRS in Metabolic & Neurodegenerative Diseases
T.B.A.
09:30
MRS of the Body: Liver, Cardiac, Muscle, etc.
T.B.A.
09:50
Clinical Integration of MRS in Radiological Workflow
T.B.A.
10:10
Proffered Papers - Oral Session
10:40
Break & Speaker Upload Available
11:20
Keynote Address: Molecular Imaging: Breaking Barriers
T.B.A.
12:00
Lunch & Speaker Upload Available
Poster Viewing
13:30
Poster Session
Session 7: Molecular Imaging
Moderator: T.B.A.
14:00
Chemical Exchange Saturation Transfer
T.B.A.
14:20
Positron Emission Tomography
T.B.A.
14:40
Single Photon Emission Computed Tomography
T.B.A.
15:00
Near Infrared Spectroscopy
T.B.A.
15:20
Fluorescence Lifetime Imaging
T.B.A.
15:40
Break & Speaker Upload Available
16:10
Special Guest: Next Generation MRI & Unmet Clinical Needs
T.B.A.
16:40
Shark-Tank Session
18:00
Tour of the Martinos Center (No CME Available)
18:30
Adjourn
Day 4 - Friday, 18 October 2024
07:30
Registration & Speaker Upload Available
Session 8: Metabolomics
Moderators: T.B.A.
08:30
NMR Spectroscopy of Tissue Extracts
T.B.A.
08:50
High-Resolution Magic Angle Spinning (HRMAS)
T.B.A.
09:10
Cellular Metabolomics by NMR & Machine-Learning
T.B.A.
09:30
Mass Spectrometry & In Vivo Microdialysis
T.B.A.
09:50
Multimodal Imaging Platform for Drug Development
T.B.A.
10:10
Infrared & Raman Spectroscopy
T.B.A.
10:30
Break & Speaker Upload Available
11:00
Code & Data Sharing Committee (No CME Available)
T.B.A.
11:30
MRS Challenge
12:00
Conclusions
12:30
Boxed Lunch & Adjourn