|
DAY 1 - Thursday, 6 November 2014 (no CME available) |
|
|
|
|
|
|
|
15:00 |
|
|
Registration & Speaker Upload Available until 18:00 |
|
|
18:00 |
|
|
Welcome
Opening
Reception |
|
| |
|
|
|
|
|
|
DAY 2 - Friday, 7 November 2014 (6.00 CME available) |
|
|
|
|
|
|
|
07:00 |
|
|
Registration
& Speaker Upload Available until 08:30; Breakfast served
until 09:00 |
|
08:30 |
|
 |
Welcome |
|
|
|
|
|
|
|
|
|
|
|
Session 1: MR & PET: Impact on Cancer Staging
|
|
|
|
|
Moderators: Paula J. Foster, Ph.D.
&
Donna H. Murrell, B.Sc.(Hons) |
|
|
09:00 |
 |
|
PET/MRI:
Facts & Fictions |
Gustav K. von
Schulthess, M.D., Ph.D.
University Hospital Zürich
Zürich, Switzerland |
|
09:30 |
|
|
Prostate
Cancer Metabolic Imaging |
Claudia Testa,
Ph.D.
University of Bologna
Bologna, Italy |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
09:45
|
|
|
The
Utility of High b-Value Diffusion Weighted MRI in Predicting
High Grade Prostate Cancers in the Peripheral Zone |
Harsh K.
Agarwal, Ph.D.
Philips Research
Bethesda, MD, USA |
|
10:00
|
|
|
Feasibility of Simultaneous 18F-FACBC PET/MRI in High Risk
Prostate Cancer Patients |
Kirsten
Margrete Selnæs, Ph.D.
Norwegian University of Science & Technology
Trondheim, Norway |
|
10:15
|
|
|
Pilot
Study: MRI Changes Associated with Dutasteride & Finasteride
Treatments in Patients with Low Risk Prostate Cancer |
Olga
Starobinets, M.Sc.
University of California
San Francisco, CA, USA |
|
10:30 |
|
|
Break |
|
|
|
|
|
|
|
|
|
|
|
Session 2: Detecting
Cancer Initiating Cells; Circulating Cancer Cells & Cancer
Dormancy |
|
|
|
|
Moderators: Kristine Glunde, Ph.D. & Amanda M. Hamilton,
Ph.D. |
|
|
11:00 |
|
|
In
Vivo Magnetic Resonance Imaging of Cells in Parenchymal
& Vascular Compartments: Opportunities & Challenges |
Piotr Walczak,
M.D., Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA |
|
11:30 |
|
|
MicroNMR
Technology for Cancer Detection
- permission withheld |
Hakho
Lee, Ph.D.
Harvard University
Cambridge, MA, USA |
|
|
|
|
Proffered
Papers – Oral Session |
|
|
11:45 |
|
|
Nanoparticles Coated with the Tumor-Penetrating Peptide iRGD
Inhibit Experimental Breast Cancer Metastasis to the Brain
|
Amanda M.
Hamilton, Ph.D.
Robarts Research Institute
London, ON, Canada |
|
12:00 |
|
|
Development of Quantitative Multi-Parametric MRI Models for
Prostate Cancer Detection using Registered Correlative
Pathology |
Gregory
J. Metzger, Ph.D.
University of Minnesota
Minneapolis, MN, USA |
|
12:15
|
|
|
Imaging
Based, Histology Trained Maps (IBHTMS) of Brain Tumor
Cellularity Predict Tumor Presence In Pathologically
Confirmed Regions Sampled Ex-Vivo |
Peter S.
LaViolette, Ph.D.
Medical College of Wisconsin
Milwaukee, WI, USA |
|
12:30 |
|
|
Lunch &
Speaker Upload Available |
|
|
|
|
|
|
|
|
|
|
|
Session 3: Tumor
Microenvironment – Interplay Between Cancer Cells,
Macrophages, Vasculature & Hypoxia
Moderators: Arvind P. Pathak, Ph.D. & Asif Rizwan, Ph.D. |
|
14:00 |
|
|
MR
Imaging of the Tumor Microenvironment
- permission withheld |
Heike Daldrup-Link,
M.D., Ph.D.
Lucile Packard Children’s Hospital
Stanford, CA, USA |
|
14:30 |
|
|
MR
Imaging to Improve Our Understanding of How the Tumor
Micro-Environment Promotes Progression & Obstructs Treatment
|
Moriel H.
Vandsburger, Ph.D.
University of Kentucky
Lexington, KY, USA |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
14:45
|
|
|
Prediction of Treatment Response in Pancreatic Cancer Using
EPR Oxygen Imaging |
Murali K.
Cherukuri, Ph.D.
National Institutes of Health
Bethesda, MD, USA |
|
15:00 |
|
|
Combined
Magnetic Resonance Spectroscopy & Mass Spectrometric Imaging
of Hypoxia |
Asif
Rizwan, Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA |
|
15:15
|
|
|
Quantitative Oxygen-Enhanced Magnetic Resonance Imaging (OE-MRI)
Biomarkers of Tumor Response to Radiation |
Derek
White, M.Sc.
University of Texas Southwestern Medical Center
Dallas, TX, USA |
|
15:30 |
|
|
Break &
Speaker Upload Available |
|
|
|
|
|
|
|
|
|
|
|
Session 4: Cancer
Treatment Response: Can MR Aid in Adaptive Therapy?
Moderators: Patrick Bolan, Ph.D. & Nassim Tayari, M.Sc. |
|
16:00 |
|
|
Imaging
of the Treatment Response in Cancer: From Cytotoxic Agents
to Signal Transduction Inhibitors |
Natalie J.
Serkova, Ph.D.
University of Colorado
Denver, CO, USA |
|
16:30 |
|
|
Selective
Acidification & De-Energization of Tumors with Lonidamine
for Sensitization to Chemotherapy |
Kavindra Nath,
Ph.D.
University of Pennsylvania
Philadelphia, PA, USA |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
16:45
|
|
|
MRI of
Liposomal Delivery of SPIO Nanoparticles to Breast Cancer
Models |
Dmitri
Artemov, Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA |
|
17:00
|
|
|
Insights
from a Gamma Knife® Radiation Necrosis Mouse Model
|
Carlos J.
Perez-Torres, Ph.D.
Washington University
St. Louis, MO, USA |
|
17:15 |
|
|
Detection
of Tumor Progression in Patients with Glioblastomas using
DTI & DSC-MRI |
Sumei
Wang, M.D.
University of Pennsylvania
Philadelphia, PA, USA |
|
17:30
|
|
|
Adjournment |
|
|
|
|
|
|
|
|
19:00 |
|
|
Dinner |
|
|
|
|
|
|
|
| |
|
|
|
|
|
|
DAY 3 - Saturday, 8 November 2014 (6.75 CME available) |
|
|
|
|
|
|
|
07:00 |
|
|
Registration, Speaker Upload Available & Breakfast Served
until 08:30 |
|
|
08:25 |
|
|
Introduction to Negendank Lecture |
|
|
08:30 |
|
|
Negendank
Lecture: Imaging Lipids & What They Can Tell Us About Cancer |
E. Jim
Delikatny, Ph.D.
University of Pennsylvania
Philadelphia, PA, USA |
|
09:15 |
|
|
Break &
Speaker Upload Available |
|
|
|
|
|
|
|
|
|
|
|
Session 5:
Spectroscopy in Clinical Cancer: Are We There Yet?
Moderators: Marnix C. Maas, Ph.D. &
Harish
Poptani, Ph.D. |
|
09:30 |
|
|
Clinical
Applications of MRS in Oncology: Problems & Progress |
Peter B. Barker,
D.Phil.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA |
|
10:00 |
|
|
1H-MRSI
in Prostate Cancer Management: Opportunities, Challenges &
Developments |
Marnix C. Maas,
Ph.D.
Radboud University
Nijmegen, The Netherlands |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
10:15
|
|
|
Evaluation of Lipid Composition in the Breast Using Multiple
Gradient Echo MRI |
Melanie
Freed, Ph.D.
NYU School of Medicine
New York, NY, USA |
|
10:30
|
|
|
Absolute
Choline Concentration Mapping for Prostate Cancer
Localization Using Water Unsuppressed 1H MR Spectroscopy
|
Nassim
Tayari, M.Sc.
Radboud University Medical Centre
Nijmegen, Netherlands |
|
10:45 |
|
|
High
Resolution Whole Brain 3D Echo Planar Spectroscopic Imaging
for Detection of Pseudo-Progression in Gliobastoma Patients |
Gaurav
Verma, Ph.D.
University of Pennsylvania
Philadelphia, PA, USA |
|
11:00 |
|
|
Break &
Speaker Upload Available |
|
|
11:15 |
|
|
Poster Session
(no CME available) |
|
|
13:00 |
|
|
Lunch &
Speaker Upload Available |
|
|
|
|
|
|
|
|
|
|
|
Session 6:
Heteronuclear & 2D NMR in Cancer Revisited -
Clinical/Pre-Clinical
Moderators: Henk M. De Feyter, Ph.D. & E. Jim
Delikatny, Ph.D. |
|
14:00 |
|
|
Biochemical Characterization of Cancer Using
Multi-dimensional MR Spectroscopic Imaging |
M. Albert
Thomas, Ph.D.
David Geffen School of Medicine
Los Angeles, CA, USA |
|
14:30
|
|
|
Non-Proton MR Imaging |
Armin Michael
Nagel, Dr.Rer.Nat.
German Cancer Research Center
Heidelberg, Germany |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
14:45 |
|
|
Detection
of Intra- & Extracellular Lactate in Cell Suspensions with
Hyperpolarized 13C NMR |
Vincent
Breukels, Ph.D.
Radboud University Medical Centre
Nijmegen, Netherlands |
|
15:00 |
|
|
Oxidative
Ketone Body Metabolism in Rat Brain Tumors & the Effect of
the Ketogenic Diet: Evidence from In Vivo 13C MRS |
Henk M.
De Feyter, Ph.D.
Yale University
New Haven, CT, USA |
|
15:15 |
|
|
Real Time
Measurement of Hyperpolarized Lactate Production & Efflux as
a Biomarker of Tumor Aggressiveness in a MR Compatible 3D
Cell & Tissue Culture Bioreactor |
Renuka
Sriram, Ph.D.
University of California
San Francisco, CA, USA |
|
15:30 |
|
|
Break &
Speaker Upload Available |
|
|
|
|
|
|
|
|
|
|
|
Session 7: Cancer MRI/MRS
at 7T – Potential & Challenges
Moderators: Tom W. J. Scheenen, Ph.D. & Gaurav Verma, Ph.D. |
|
16:00 |
|
|
Cancer
MRI/MRS at 7T – Potential & Challenges |
Dennis W. J.
Klomp, Ph.D.
University Medical Center Utrecht
Malden, The Netherlands |
|
16:30 |
|
|
7T MRI/MRS
When Imaging the Effects of Therapy of Brain Tumors |
Janine M. Lupo,
Ph.D.
University of California
San Francisco, CA, USA |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
16:45
|
|
|
Combined
PGSE & OGSE DWI for Characterization of Extracellular Space
(ECS) in GL261 GBM Model |
Olivier
Reynaud, Ph.D.
NYU Langone Medical Center
New York, NY, USA |
|
17:00
|
|
|
Advancing
the Early Detection & Diagnosis of Primary & Recurring
Thyroid Cancers Using a Molecularly Targeted T2-Exchange MRI
Contrast Agent |
Todd C.
Soesbe, Ph.D.
University of Texas Southwestern Medical Center
Dallas, TX, USA |
|
17:15 |
|
|
Assessment of Membrane Fluidity Using Nuclear Overhauser
Enhancement Mediated Magnetization Transfer (NOE-Mediated
MT) |
Xiaoyong
Zhang, Ph.D.
Vanderbilt University
Nashville, TN, USA |
|
|
|
|
|
|
|
17:30 |
|
|
Session 8: Working
Group Sessions |
|
|
|
|
|
• High Field
MRI/MRS
• Diffusion MRI – Data Acquisition & Analysis
• Perfusion Imaging – Data Acquisition & Analysis
• Novel Contrast Including MTR, CEST & APT
• Integrating MRI/MRS in Clinical Trials |
|
|
18:15 |
|
|
Adjournment |
|
|
|
|
|
|
|
|
19:00 |
|
|
Dinner
Banquet |
|
|
|
|
|
|
|
| |
|
|
|
|
|
|
DAY 4 –
Sunday, 9 November 2014 (3.00 CME available) |
|
|
|
|
|
|
|
07:00 |
|
|
Registration, Speaker Upload Available & Breakfast Served
until 08:30 |
|
|
|
|
|
|
|
|
08:25 |
|
|
Young
Investigator Poster Awards |
|
|
|
|
|
|
|
|
|
|
|
Session 9: Emerging
Contrast Mechanisms for Cancer Imaging
Moderators: Joel R. Garbow, Ph.D. & Ashley Stokes, Ph.D. |
|
08:30 |
|
|
Can MR
Contrast Agents Compete with Other Modalities for Molecular
Imaging of Cancer? |
A. Dean Sherry,
Ph.D.
UT Southwestern Medical Center
Dallas, TX, USA |
|
09:00 |
|
|
Non-Invasive Redox CEST MRI as a Potential Endogenous Imaging
Biomarker for In Vivo Redox States |
Kejia Cai, Ph.D.
University of Illinois
Chicago, IL, USA |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
09:15
|
|
|
Feasibility & Reproducibility of R2* & R1 Measurements Under
Oxygen & Carbogen Challenge in Healthy Volunteers & Patients
with Hepatocellular Carcinoma at 1.5 T & 3T |
Octavia
Bane, Ph.D.
Icahn School of Medicine at Mount Sinai
New York, NY, USA |
|
09:30
|
|
|
Characterization of Cancer Onset & Development using
Diffusion Weighted MRI in a Transgenic Mouse Model of
Prostate Cancer |
Deborah
K. Hill, Ph.D.
Norwegian University of Science & Technology
Trondheim, Norway |
|
09:45
|
|
|
MR
Elastography in Glioma: Feasibility & Initial Comparison
with Tumor Grade |
Kay M.
Pepin, B.Sc.
Mayo Clinic
Rochester, MN, USA |
|
10:00 |
|
|
Break &
Speaker Upload Available |
|
|
|
|
|
|
|
|
|
|
|
Session 10: New
Perspectives in Cancer Metabolism
Moderators:
Deborah
K. Hill, Ph.D. & Kayvan R. Keshari, Ph.D. |
|
10:30 |
|
|
Magnetic Resonance Spectroscopy Studies of Mutant IDH Cells |
Sabrina M.
Ronen, Ph.D.
University of California
San Francisco, CA, USA |
|
11:00 |
|
|
The
Potential & Challenges of High Resolution Magic Angle
Spinning MR in Characterization of Breast Cancer |
Maria Dung Cao,
Ph.D.
Norwegian University of Science & Technology
Trondheim, Norway |
|
|
|
|
Proffered Papers
– Oral Session |
|
|
11:15 |
|
|
Dual-Modality Molecular Imaging of Choline Kinase
Expression & Inhibition in a Breast Cancer Model |
Sean P.
Arlauckas, B.S.E.
University of Pennsylvania
Philadelphia, PA, USA |
|
11:30 |
|
|
Combining Magnetic Resonance Spectroscopic Imaging &
Mass Spectrometric Imaging Reveals Protein Biomarkers of
Aggressive Breast Cancer |
Lu Jiang,
Ph.D.
Johns Hopkins Univ. School of Medicine
Baltimore, MD, USA |
|
11:45 |
|
|
Pretherapeutic Lactate Levels Measured by MR-Spectroscopy
Can Predict the Pattern of Progression in Recurrent
Glioblastoma Under Antiangiogenic Therapy with Bevacizumab |
Katharina
J. Wenger, M.D.
University Hospital Frankfurt
Frankfurt, Germany |
|
12:00 |
|
|
Adjournment/Boxed Lunches |
|
|
|
|
|
|
|
|
|
|
|
|
|